Development of an applicationfor individualized Warfarin treatment: Independent Project in Engineering Physics
Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
A problem with the widley usedanticoagulant medicine Warfarin hasalways been that the therapeutic dosevaries from person to person and thatthere has not been any methods toestimate individually-based dosingregimens. By using a new populationmodeldescribing the relationship betweenWarfarin dose and INR(internationalnormalized ratio) response fordifferent individuals based on their age,weight and genotypes, a user friendly,dose estimating program has beendeveloped in Java. The applicationestimates the INR given the individualparameters and dosing, but it's alsopossible to estimate the predicted dosegiven the desired INR. The applicationmakes it possible for others to take partof the model, and to give a moreindividualized Warfarin treatment inclinical practice.
Place, publisher, year, edition, pages
2012. , 7 p.
TVE, 12 049 augusti
Warfarin, Waran, Java, Swing, Netbeans, KPD
Engineering and Technology
IdentifiersURN: urn:nbn:se:uu:diva-180358OAI: oai:DiVA.org:uu-180358DiVA: diva2:549581
Master Programme in Engineering Physics
2012-05-29, Å4006, Ångströmslaboratoriet, Uppsala, 21:24 (Swedish)