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Development of an applicationfor individualized Warfarin treatment: Independent Project in Engineering Physics
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences.
Uppsala University, Disciplinary Domain of Science and Technology, Technology, Department of Engineering Sciences.
2012 (English)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

A problem with the widley usedanticoagulant medicine Warfarin hasalways been that the therapeutic dosevaries from person to person and thatthere has not been any methods toestimate individually-based dosingregimens. By using a new populationmodeldescribing the relationship betweenWarfarin dose and INR(internationalnormalized ratio) response fordifferent individuals based on their age,weight and genotypes, a user friendly,dose estimating program has beendeveloped in Java. The applicationestimates the INR given the individualparameters and dosing, but it's alsopossible to estimate the predicted dosegiven the desired INR. The applicationmakes it possible for others to take partof the model, and to give a moreindividualized Warfarin treatment inclinical practice.

Place, publisher, year, edition, pages
2012. , 7 p.
Series
TVE, 12 049 augusti
Keyword [en]
Warfarin, Waran, Java, Swing, Netbeans, KPD
National Category
Engineering and Technology
Identifiers
URN: urn:nbn:se:uu:diva-180358OAI: oai:DiVA.org:uu-180358DiVA: diva2:549581
External cooperation
Anna-Karin Hamberg
Educational program
Master Programme in Engineering Physics
Presentation
2012-05-29, Å4006, Ångströmslaboratoriet, Uppsala, 21:24 (Swedish)
Uppsok
Technology
Supervisors
Examiners
Available from: 2012-10-05 Created: 2012-09-04 Last updated: 2012-10-05Bibliographically approved

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Development of an applicationfor individualized Warfarin treatment(816 kB)494 downloads
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Type fulltextMimetype application/pdf

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CiteExportLink to record
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Citation style
  • apa
  • ieee
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Output format
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