Self-reported versus true adherence in heart failure patients: a study using the Medication Event Monitoring System
2012 (English)In: NETHERLANDS HEART JOURNAL, ISSN 1568-5888, Vol. 20, no 7-8, 313-319 p.Article in journal (Refereed) Published
Adherence to (non)pharmacological treatment is important in heart failure (HF) patients, since it leads to better clinical outcome. Although self-reported and objectively measured medication adherence in HF patients have been compared in previous studies, none of these studies have used an evidence-based cutpoint to differentiate between adherence and non-adherence. In 37 HF patients (mean age 68 +/- 10 years, 27 % female, 40 % NYHA functional class III-IV), medication (ACEi/ARB) adherence was objectively measured using the Medication Event Monitoring System (MEMS). Adherence to and importance of taking medication was also assessed by self-report using the Revised HF Compliance Questionnaire. All patients reported that adherence was (highly) important to them and that they always took their medication as prescribed (i.e. 100 % adherence). However, when measured by the MEMS, only 76 % of all patients were adherent. Non-adherent patients more often had a complex medication regimen (78 % vs. 21 %, P less than .01), more often depressive symptoms (75 % vs. 29 %, P = .04) and a shorter history of HF (8 vs. 41 months, P = .04), compared with adherent patients. Medication adherence measured by the MEMS was remarkably lower than self-reported adherence. Given the evidence of its importance, further efforts are needed to improve adherence to the pharmacological regimen in HF patients.
Place, publisher, year, edition, pages
Springer Verlag (Germany) , 2012. Vol. 20, no 7-8, 313-319 p.
Adherence; Compliance; Heart failure; Medication event monitoring system; Self-report
Medical and Health Sciences
IdentifiersURN: urn:nbn:se:liu:diva-80694DOI: 10.1007/s12471-012-0283-9ISI: 000306736500005OAI: oai:DiVA.org:liu-80694DiVA: diva2:547834