Change search
ReferencesLink to record
Permanent link

Direct link
Immigrant status and increased risk of heart failure: the role of hypertension and life-style risk factors
Department of Clinical Sciences, Cardiovascular Epidemiology, Lund University, Malmö, Sweden.
Department of Clinical Sciences, Cardiovascular Epidemiology, Lund University, Malmö, Sweden.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health. (Internationell kvinno- och mödrahälsovård och migration/Essén)
Department of Clinical Sciences, Cardiovascular Epidemiology, Lund University, Malmö, Sweden.
2012 (English)In: BMC Cardiovascular Disorders, ISSN 1471-2261, Vol. 12, 20- p.Article in journal (Refereed) Published
Abstract [en]


Studies from Sweden have reported association between immigrant status and incidence of cardiovascular diseases. The nature of this relationship is unclear. We investigated the relationship between immigrant status and risk of heart failure (HF) hospitalization in a population-based cohort, and to what extent this is mediated by hypertension and life-style risk factors. We also explored whether immigrant status was related to case-fatality after HF.


26,559 subjects without history of myocardial infarction (MI), stroke or HF from the community-based Malmo Diet and Cancer (MDC) cohort underwent a baseline examination during 1991-1996. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years.


3,129 (11.8%) subjects were born outside Sweden. During follow-up, 764 subjects were hospitalized with HF as primary diagnosis, of whom 166 had an MI before or concurrent with the HF. After adjustment for potential confounding factors, the hazard ratios (HR) for foreign-born were 1.37 (95% CI: 1.08-1.73, p = 0.009) compared to native Swedes, for HF without previous MI. The results were similar in a secondary analysis without censoring at incident MI. There was a significant interaction (p < 0.001) between immigrant status and waist circumference (WC), and the increased HF risk was limited to immigrants with high WC. Although not significant foreign-born tended to have lower one-month and one-year mortality after HF.


Immigrant status was associated with long-term risk of HF hospitalization, independently of hypertension and several life-style risk factors. A significant interaction between WC and immigrant status on incident HF was observed.

Place, publisher, year, edition, pages
2012. Vol. 12, 20- p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:uu:diva-172797DOI: 10.1186/1471-2261-12-20ISI: 000302898300001PubMedID: 22443268OAI: diva2:515784
Available from: 2012-04-16 Created: 2012-04-16 Last updated: 2013-07-22Bibliographically approved

Open Access in DiVA

fulltext(248 kB)72 downloads
File information
File name FULLTEXT01.pdfFile size 248 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Essén, Birgitta
By organisation
Department of Women's and Children's Health
In the same journal
BMC Cardiovascular Disorders
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 72 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 323 hits
ReferencesLink to record
Permanent link

Direct link