Digitala Vetenskapliga Arkivet

Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The COACH risk engine: a multistate model for predicting survival and hospitalization in patients with heart failure
University of Groningen.
University of Groningen.
Linköping University, Department of Social and Welfare Studies, Health, Activity, Care. Linköping University, Faculty of Health Sciences.ORCID iD: 0000-0002-4197-4026
University of Groningen.
Show others and affiliations
2012 (English)In: European Journal of Heart Failure, ISSN 1388-9842, E-ISSN 1879-0844, Vol. 14, no 2, p. 168-175Article in journal (Refereed) Published
Abstract [en]

Aims Several models for predicting the prognosis of heart failure (HF) patients have been developed, but all of them focus on a single outcome variable, such as all-cause mortality. The purpose of this study was to develop a multistate model for simultaneously predicting survival and HF-related hospitalization in patients discharged alive from hospital after recovery from acute HF. less thanbrgreater than less thanbrgreater thanMethods and results The model was derived in the COACH (Coordinating Study Evaluating Outcomes of Advising and Counseling in Heart Failure) cohort, a multicentre, randomized controlled trial in which 1023 patients were enrolled after hospitalization because of HF. External validation was attained with the FINN-AKVA (Finish Acute Heart Failure Study) cohort, a prospective, multicentre study with 620 patients hospitalized due to acute HF. The observed vs. predicted 18-month survival was 72.1% vs. 72.3% in the derivation cohort and 71.4% vs. 71.2% in the validation cohort. The corresponding values of the c statistic were 0.733 [95% confidence interval (CI) 0.705-0.761] and 0.702 (95% CI 0.663-0.744), respectively. The models accuracy in predicting HF hospitalization was excellent, with predicted values that closely resembled the values observed in the derivation cohort. less thanbrgreater than less thanbrgreater thanConclusion The COACH risk engine accurately predicted survival and various measures of recurrent hospitalization in (acute) HF patients. It may therefore become a valuable tool in improving and personalizing patient care and optimizing the use of scarce healthcare resources.

Place, publisher, year, edition, pages
Oxford University Press (OUP): Policy B , 2012. Vol. 14, no 2, p. 168-175
Keywords [en]
Epidemiology, Heart failure, Prediction, Prognosis, Multistate modelling
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-75105DOI: 10.1093/eurjhf/hfr163ISI: 000299350800010OAI: oai:DiVA.org:liu-75105DiVA, id: diva2:504553
Note
Funding Agencies|Center for Translational Molecular Medicine (CTMM)|01C-103|Dutch Heart Foundation|2000Z003D97.017|Novartis (Arnhem, The Netherlands)||Available from: 2012-02-21 Created: 2012-02-17 Last updated: 2019-06-27

Open Access in DiVA

fulltext(336 kB)913 downloads
File information
File name FULLTEXT01.pdfFile size 336 kBChecksum SHA-512
48cab22f1ca0d62e212d58ef6ab87dc024f939f4d8242161627a8c1003c493b76c040cf7a51965ad75a3a30a4cf69795db40a5e9c5e13874b59f2a66405434a0
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Jaarsma, Tiny
By organisation
Health, Activity, CareFaculty of Health Sciences
In the same journal
European Journal of Heart Failure
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 913 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 442 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf