Three dimensional asymmetric microenvironment for cell biological studies
2005 (English)In: Proceedings of µTAS 2005 Conference, 2005, 915-917 p.Conference paper (Refereed)
We report on a method for three-dimensional cultivation of cells in a microstructured asymmetric environment. In the system an asymmetric environment is created by using diffusion through a gel of extra cellular matrix proteins surrounded by microfluidic flow channels. Individual cells embedded in the gel react on the concentration gradient. The system has been evaluated both for diffusion properties and based on the cellular response.
Place, publisher, year, edition, pages
2005. 915-917 p.
Cell culture, diffusion barrier, flow-through, gradient
Engineering and Technology
IdentifiersURN: urn:nbn:se:kth:diva-77798ScopusID: 2-s2.0-84902475284ISBN: 0-9743611-1-9OAI: oai:DiVA.org:kth-77798DiVA: diva2:492086
9th International Conference on Miniaturized Systems for Chemistry and Life Sciences October 9-13, 2005, Boston, Massachusetts, USA