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Changes in Erythrocyte Sedimentation Rate, White Blood Cell Count, Liver Enzymes, and Magnesium after Gastric Bypass Surgery
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics. (Lars Lannfelt)
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Geriatrics.
2011 (English)In: Journal of Obesity, ISSN 2090-0708, E-ISSN 2090-0716, Vol. 2011, 273105- p.Article in journal (Refereed) Published
Abstract [en]

Roux-en-Y gastric bypass (RYGBP) is an established method for treatment of obesity, a condition of chronic inflammation with liver steatosis, characterised by increased erythrocyte sedimentation rate (ESR), white blood cell count (WBC), liver enzymes, and decreased magnesium (Mg).We investigated alterations, if any, in ESR, WBC, alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), and Mg after RYGBP. Methods. 21 morbidly obese nondiabetic patients who underwent RYGBP surgery were evaluated preoperatively (baseline), then 1 year (1st followup) and 3.5 years (2nd followup) after RYGBP and compared to an untreated control group. Results. Body mass index, ESR, WBC, ALT, and GGT were all significantly reduced at 1 year in the RYGBP group (30%, 35%, 20%, 45%, and 57%, resp.) while Mg increased by 6%, compared to control group (P = 0.001 − 0.009). Conclusions. Obese patients treated by RYGBP show sustained reductions in ESR, WBC, ALT, and GGTpossibly due to reduced liver steatosis and increased Mg.

Place, publisher, year, edition, pages
Hindawi Publishing Corporation, 2011. Vol. 2011, 273105- p.
Keyword [en]
Erythrocyte sedimentation rate, White blood cell count, Gatric bypass
National Category
Surgery
Research subject
Medical Science
Identifiers
URN: urn:nbn:se:uu:diva-165449DOI: 10.1155/2011/273105OAI: oai:DiVA.org:uu-165449DiVA: diva2:473774
Available from: 2012-01-09 Created: 2012-01-07 Last updated: 2017-12-08Bibliographically approved

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