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15-year efficacy of uvulopalatopharyngoplasty based on objective and subjective data
Karolinska University Hospital.
Karolinska University Hospital.
Linköping University, Department of Clinical and Experimental Medicine, Clinical Neurophysiology. Linköping University, Faculty of Health Sciences. Östergötlands Läns Landsting, Sinnescentrum, Department of Neurophysiology UHL.
Karolinska University Hospital.
2011 (English)In: Acta Oto-Laryngologica, ISSN 0001-6489, Vol. 131, no 12, 1303-1310 p.Article in journal (Refereed) Published
Abstract [en]

Conclusions: This follow-up showed a stable and significant decrease in median oxygen desaturation index 4% (ODI(4)) values over the years. Approximately two-thirds of the patients fulfilled the success criteria (ODI4 reduction of 50% and andlt;20) after 15 years. A majority had improved/cured excessive daytime sleepiness (EDS) and were satisfied. No increased mortality rate was seen. Objectives: To evaluate sleep apnoea recordings and symptoms in patients with obstructive sleep apnoea syndrome 15 years after uvulopalatopharyngoplasty (UPPP) compared to baseline and previous follow-ups. Methods: This was a non-randomized, prospective intervention study on 50 patients who underwent UPPP during 1985-88. Their initial median age was 49 years (range 38-71) and ODI4 was 26.5 (4-82). Results: In all, 13 patients had died; 26 patients underwent sleep apnoea recordings. Median ODI4 had decreased from 26.5 (range 4-82) to 8.5 (0-60), p andlt; 0.01, a mean reduction of 52%; 65% of patients achieved the success criteria. One-third was objectively categorized as non-snorers. Median body mass index was unchanged. The questionnaires were answered by 32 of 37 patients; 88% reported improved or cured EDS and 78% were satisfied. Pharyngeal disturbances ratings were low. The standardized mortality rate did not differ from the general Swedish population.

Place, publisher, year, edition, pages
Informa Healthcare , 2011. Vol. 131, no 12, 1303-1310 p.
Keyword [en]
Sleep apnoea, obstructive sleep apnoea, OSA, obstructive sleep apnoea syndrome, OSAS, pharyngeal surgery
National Category
Medical and Health Sciences
URN: urn:nbn:se:liu:diva-72804DOI: 10.3109/00016489.2011.616912ISI: 000296886700010OAI: diva2:463288
Funding Agencies|Swedish Association of Sleep Medicine and Sleep Research||Acta Otolaryngologica Foundation||Available from: 2011-12-09 Created: 2011-12-08 Last updated: 2011-12-20

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Svanborg, Eva
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Clinical NeurophysiologyFaculty of Health SciencesDepartment of Neurophysiology UHL
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