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Hemodynamic Model of the Cardiovascular System during Valsalva Maneuver and Orthostatic Changes
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
2011 (English)Independent thesis Advanced level (professional degree), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

The goal of the Master's Thesis was to extend an existing cardiovascular model to include the mechanics of the lung, thus allowing to simulate breathing maneuvers such as the Valsalva maneuver and the Forced Vital Capacity maneuver. This included a remodeling of the pulmonary capillaries and of the existing interactions of the model with the intrathoracic pressure. The existing description of the vascular compartments was found to be insufficient to describe the hemodynamic response to orthostatic changes and was extended to include a compartment representing the upper body. Stress relaxation was included into all the larger vascular compartments. The results showed an improved accuracy of the extended model when subjected to large intrathoracic pressure changes and during orthostatic stress. The internal responses of the newly modeled pulmonary capillaries were studied and verified against literature with satisfying results.

Place, publisher, year, edition, pages
2011. , 89 p.
Keyword [en]
Hemodynamics, model, Valsalva, cardiovascular
National Category
Other Medical Engineering
URN: urn:nbn:se:umu:diva-50044OAI: diva2:458759
Subject / course
Examensarbete i teknisk fysik
Educational program
Master of Science Programme in Engineering Physics
2011-11-11, Universitetsklubben, Umeå Universitet, Umeå, 13:40 (English)
Available from: 2013-08-09 Created: 2011-11-23 Last updated: 2013-08-09Bibliographically approved

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