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Wireless Remote Monitoring of Glucose Using a Functionalized ZnO Nanowire Arrays Based Sensor
Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
Linköping University, Department of Science and Technology. Linköping University, The Institute of Technology.
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2011 (English)In: Sensors, ISSN 1424-8220, Vol. 11, no 9, 8485-8496 p.Article in journal (Refereed) Published
Abstract [en]

This paper presents a prototype wireless remote glucose monitoring system interfaced with a ZnO nanowire arrays-based glucose sensor, glucose oxidase enzyme immobilized onto ZnO nanowires in conjunction with a Nafion (R) membrane coating, which can be effectively applied for the monitoring of glucose levels in diabetics. Global System for Mobile Communications (GSM) services like General Packet Radio Service (GPRS) and Short Message Service (SMS) have been proven to be logical and cost effective methods for gathering data from remote locations. A communication protocol that facilitates remote data collection using SMS has been utilized for monitoring a patients sugar levels. In this study, we demonstrate the remote monitoring of the glucose levels with existing GPRS/GSM network infra-structures using our proposed functionalized ZnO nanowire arrays sensors integrated with standard readily available mobile phones. The data can be used for centralized monitoring and other purposes. Such applications can reduce health care costs and allow caregivers to monitor and support to their patients remotely, especially those located in rural areas.

Place, publisher, year, edition, pages
MDPI , 2011. Vol. 11, no 9, 8485-8496 p.
Keyword [en]
electrochemical nanosensor, ZnO nanowires, glucose oxidase, Nafion (R) membrane, remote monitoring, data acquisition, Global System for Mobile Communications (GSM)
National Category
Engineering and Technology
URN: urn:nbn:se:liu:diva-71798DOI: 10.3390/s110908485ISI: 000295211700017OAI: diva2:453994
Available from: 2011-11-04 Created: 2011-11-04 Last updated: 2014-01-15
In thesis
1. Fabrication and characterization of ZnO nanostructures for sensing and photonic device applications
Open this publication in new window or tab >>Fabrication and characterization of ZnO nanostructures for sensing and photonic device applications
2012 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Nanotechnology is an emerging inter-disciplinary paradigm which encompasses diverse fields of science and engineering converge at the nanoscale. This nanoscale science and nanostructure engineering have well demonstrated in the fabrication of sensors/transducers devices with faster response time and better sensitivity then the planer version of the sensor’s configurations. Nanotechnology is not just to grow/fabricate nanostructures by just mixing nanoscale materials together but it requires the ability to understand and to precisely manipulate and control of the developed nanomaterials in a useful way. Nanotechnology is aiding to substantially improve, even revolutionize, many technology and industry sectors like information technology, energy, environmental science, medicine/medical instrumentation, homeland security, food safety, and transportation, among many others. Such applications of nanotechnology are delivering in both expected and unexpected ways on nanotechnology’s promise to benefit the society.

The semiconductor ZnO with wide band gap (~ 3.37 eV) is a distinguish and unique material and its nanostructures have attracted great attention among the researchers due to its peculiar properties such as large exciton binding energy (60 meV) at room temperature, the high electron mobility, high thermal conductivity, good transparency and easiness of fabricating it in the different type of nanostructures. Based on all these fascinating properties, ZnO have been chosen as a suitable material for the fabrication of photonic, transducers/sensors, piezoelectric, transparent and spin electronics devices etc. The objective of the current study is to highlight the recent developments in materials and techniques for electrochemical sensing and hetrostructure light emitting diodes (LEDs) luminescence properties based on the different ZnO nanostructures. The sensor devices fabricated and characterized in the work were applied to determine and monitor the real changes of the chemical or biochemical species. We have successfully demonstrated the application of our fabricated devices as primary transducers/sensors for the determination of extracellular glucose and the glucose inside the human fat cells and frog cells using the potentiometric technique. Moreover, the fabricated ZnO based nanosensors have also been applied for the selective determination of uric acid, urea and metal ions successfully. This thesis relates specifically to zinc oxide nanostructure based electrochemical sensors and photonic device (LED) applications.

Place, publisher, year, edition, pages
Linköping: Linköping University Electronic Press, 2012. 76 p.
Linköping Studies in Science and Technology. Dissertations, ISSN 0345-7524 ; 1412
Nanotechnology, zinc oxide, nanowires/ nanorods, nanotubes, nanoporous/nanoflakes, electrochemical sensor and photonic devices
National Category
Electrical Engineering, Electronic Engineering, Information Engineering
urn:nbn:se:liu:diva-72774 (URN)978-91-7393-015-4 (ISBN)
Public defence
2012-01-17, K3, Kåkenhus, Campus Norrköping, Linköpings universitet, Norrköping, 10:15 (English)
Available from: 2011-12-07 Created: 2011-12-07 Last updated: 2014-01-15Bibliographically approved

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