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Assessment of the potential role of muscle spindle mechanoreceptor afferents in chronic muscle pain in the rat masseter muscle
Université de Montréal.
McGill University, Montréal.
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB), Physiology.
McGill University, Montréal.
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2010 (English)In: PLoS ONE, ISSN 1932-6203, Vol. 5, no 6, e11131- p.Article in journal (Refereed) Published
Abstract [en]

Low pH leads to changes in several electrical properties of MSA, including initiation of ectopic action potentials which could propagate centrally but could also invade the peripheral endings causing glutamate release and activation of nearby nociceptors within the spindle capsule. This peripheral drive could contribute both to the transition to, and maintenance of, persistent muscle pain as seen in some "functional" pain syndromes.

Place, publisher, year, edition, pages
Public library of science , 2010. Vol. 5, no 6, e11131- p.
Keyword [en]
dorsal-root ganglion; metabotropic glutamate receptors; primary sensory neurons; mesencephalic-v neurons; c-fos; mechanical allodynia; trigeminal neurons; neuropathic pain; jaw-muscle; group-i
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URN: urn:nbn:se:umu:diva-41333DOI: 10.1371/journal.pone.0011131ISI: 000278775900020PubMedID: 20559566OAI: diva2:405716
Available from: 2011-03-23 Created: 2011-03-23 Last updated: 2014-06-10Bibliographically approved

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Athanassiadis, TuijaWestberg, Karl-Gunnar
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