Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Microstimulation in The Brain: Does Microdialysis Influence the Activated Volume of Tissue?
University of Luebeck, Institute for Signal Processing. (Biosignal Group)ORCID iD: 0000-0002-5619-409X
University of Luebeck, Institute for Neurology.
University of Luebeck, Institute for Neurology,.
University of Luebeck, Institute for Signal Processing.
2009 (English)In: Proceedings of the COMSOL Conference Milan 2009, Milan: COMSOL , 2009, , 7 p.Conference paper, Published paper (Other academic)
Abstract [en]

Deep brain stimulation (DBS) has been established as an effective treatment for Parkinson’s disease and other movement disor- ders. The stimulation is currently administered using tetrode-macroelectrodes that target the subthalamic nucleus (STN). This often leads to side effects which bias the surrounding ar- eas, e.g. the speech centre. Targeting a spe- cific brain region can better be achieved with micro-stimulation electrodes with directed elec- trical field distribution. Experimental studies showed the effectiveness of microelectrode DBS by comparing neurotransmitter outflow before and after the stimulation. The neurotransmit- ter outflow in close proximity to the stimulation is hereby measured by means of microdialysis. To establish ideal distances and stimulation strength, the electric potential around the stim- ulation electrode and microdialysis membrane were modelled using comsol Multiphysics.

Place, publisher, year, edition, pages
Milan: COMSOL , 2009. , 7 p.
Keyword [en]
deep brain stimulation, electrode-brain interface, impedance, microdialysis, microelectrodes
National Category
Industrial Biotechnology
Identifiers
URN: urn:nbn:se:miun:diva-10625OAI: oai:DiVA.org:miun-10625DiVA: diva2:280516
Conference
COMSOL Conference Milan 2009
Available from: 2012-10-12 Created: 2009-12-10 Last updated: 2012-10-12Bibliographically approved

Open Access in DiVA

Microstimulation in The Brain—Does Microdialysis Influence the Activated Volume of Tissue?(2151 kB)632 downloads
File information
File name FULLTEXT01.pdfFile size 2151 kBChecksum SHA-512
855f82c0aa4ed863109568dc39ba69f699e07b35976e2c2d24dba3e451426e10ccbe1c8ef33c877eaa149148f92ca2051a26292df8e7d31321adfbf8a08e6325
Type fulltextMimetype application/pdf

Search in DiVA

By author/editor
Krapohl, David
Industrial Biotechnology

Search outside of DiVA

GoogleGoogle Scholar
Total: 632 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

urn-nbn

Altmetric score

urn-nbn
Total: 375 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf