Reports have indicated an increase in anti-Jewish hostility and antisemitic incidents following the Hamas terrorist attack in Israel on October 7, 2023, and the subsequent war in Gaza. In two studies (NStudy1 = 354 and NStudy2 = 490), we experimentally investigated the impact of priming with material referring to the war in Gaza on hostility toward Jews, and on antisemitism as well as other various ethnic groups (to determine whether this exposure specifically affected attitudes toward Jews or had a broader impact on ethnic attitudes in general). We also examined the indirect relationship between political orientation and anti-Jewish hostility and antisemitism, through sociopolitical factors such as global identification, out-group identity fusion, social dominance orientation, and misanthropy. Our results showed an experimental effect of increased negative attitudes toward Jews, as well as toward Britons and Scandinavians, but did not reveal an increase in antisemitism. This effect was not replicated in Study 2, possibly due to reduced media attention. The indirect effects suggested that political orientation (left vs. right-wing) was positively associated with anti-Jewish hostility and antisemitism through social dominance orientation. In contrast, conservative political orientation was negatively associated with antisemitism through out-group identity fusion with the Palestinian people. Our findings imply two distinct political pathways to antisemitism: one linked with classical political right-wing orientation and the other to a complex identity-based conflation of attitudes toward Israel with prejudice toward the Jewish ethnic group.