Introduction:Hyperbilirubinemia is a prevalent condition among newborns. In 2019, region Örebro county implemented a novel treatment method, home phototherapy, enabling treatment at home instead of the ordinary phototherapy at the hospital. Aim:The primary aim:to describe the utilization rates of home phototherapy and hospital phototherapy among newborns, along with the factors behind choice of treatment. The secondary aim:to investigate differences in length of stay between the two phototherapy methods and sex differences.Methods:Retrospective review of patient records. The study period October 2019 to March 2023. Patients were identified using ICD-codes for jaundice and immunization in two different records systems and a registry.Results:494 patients wereincluded, 52% received home phototherapy (38% primarily and 13% secondarily). 48% received hospital phototherapy,mostly due to immunization and a need for intensive phototherapy. Home phototherapy resulted in a 61hour shorter length of stay compared to hospital phototherapy(p <0,001). Male newborns had a median bilirubin level of 349 μmol/L at admission and 354 μmol/L as peak level, in female newborns the values were 340 μmol/L and 348 μmol/L, respectively (p=0,017; p=0,034).Conclusions:52%of the newborns were eligible for treatment with home phototherapy. The most common causes for hospitalization were immunization and a need for intensive phototherapy.