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The experienced route to cognitive health: Cognitive recovery in persons with prior stress-related Exhaustion disorder
Karlstad University, Faculty of Arts and Social Sciences (starting 2013), Department of Social and Psychological Studies (from 2013).ORCID iD: 0000-0002-6949-0621
Umeå University, Sweden.
Karlstad University, Faculty of Arts and Social Sciences (starting 2013), Department of Social and Psychological Studies (from 2013).ORCID iD: 0000-0002-9688-5805
Karlstad University, Faculty of Arts and Social Sciences (starting 2013), Department of Social and Psychological Studies (from 2013).ORCID iD: 0000-0003-3450-8067
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2025 (English)In: BMC Psychiatry, E-ISSN 1471-244X, Vol. 25, article id 375Article in journal (Refereed) Published
Abstract [en]

Background

People diagnosed with stress-related exhaustion disorder report high levels of cognitive symptoms. This study aimed to explore how persons diagnosed with Exhaustion disorder (ED) experienced cognitive functioning and recovery 6-10 years after participating in a rehabilitation programme. Specifically, it investigated the experiences of current functioning, change over time, and what had been barriers or facilitators for cognitive recovery.

Methods

Semi‐structured interviews were conducted for 38 persons previously diagnosed with ED (Mean age: 52; Females: 32) and explored using thematic analysis.

Results

The analysis resulted in four themes: “’It’s different now’: Remaining cognitive symptoms”, “The bigger picture: Cognitive recovery in context”, “Overcoming challenges: Strategies for coping with cognitive symptoms”, and “The approach towards cognition matters”. The participants’ experiences varied but included descriptions on how cognitive functioning had become better with some remaining symptoms. These difficulties were reported across cognitive domains, yet often centred around upholding executive control. Cognitive recovery was seen in the context of overall well-being and recovery which differed between the participants. Facilitators and barriers thus varied between persons, and included both restorative and compensatory strategies, external conditions, the degree of worry, and development of a more acceptant or self-compassionate view on cognition and oneself.

Conclusions

The results show that cognitive recovery in ED is multifaceted. 6-10 years after rehabilitation, experiences included improvement of everyday cognitive functioning, but also lingering challenges, often related to maintenance of executive control. Recovery was influenced by factors such as general well-being, restorative or compensatory strategies, worrying, or the adaptation of more accepting or self-compassionate perspectives. The findings indicate a need for tailored, person-centred approaches to supporting cognitive recovery.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2025. Vol. 25, article id 375
National Category
Psychology
Research subject
Psychology
Identifiers
URN: urn:nbn:se:kau:diva-103753DOI: 10.1186/s12888-025-06713-7Scopus ID: 2-s2.0-105003016801OAI: oai:DiVA.org:kau-103753DiVA, id: diva2:1948326
Available from: 2025-03-28 Created: 2025-03-28 Last updated: 2025-05-02Bibliographically approved
In thesis
1. Self-reported cognition in Exhaustion Disorder: From brain to experience
Open this publication in new window or tab >>Self-reported cognition in Exhaustion Disorder: From brain to experience
2025 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Exhaustion disorder (ED) is a relatively new diagnosis associated with cognitive symptoms, which are normally assessed using standardized cognitive tests or questionnaires targeting everyday cognitive failures (i.e., subjective cognitive complaints, SCCs). The purpose of this thesis was to add empirical knowledge on the self-reported, first-hand experience of cognitive function in ED. More specifically, it aimed to learn how SCCs relate to test performance, psychological distress and neural activity. Further objectives were to evaluate the types of difficulties being expressed, and what aspects can be considered helpful or hindering with respect to cognitive recovery. 

Study 1 found that when compared to healthy controls, ED patients reported substantially higher levels of SCCs, and were more likely to express difficulties in situations without external memory cues. In both groups, the level of SCCs was correlated with psychological distress and not with cognitive test-results. Using functional magnetic resonance imaging, Study 2 investigated the relationship between SCCs, test performance and brain activity. There was no association between SCCs and behavioural results on the in-scanner task, tapping response inhibition. However, a positive correlation was detected between SCCs and relatively more brain activity in a cluster in the right-side occipital lobe during the more difficult task condition. This exploratory finding may indicate compensational neural activity, possibly involving visual processing or the altering between task positive and task negative neural networks. Study 3 analysed interviews with people who had participated in ED-rehabilitation 6-10 years earlier, and displayed a range of individual experiences. Cognitive symptoms had been highly distressing. Lingering problems were also noted in several cognitive areas, but maintenance of attention and executive control may be  domain-general areas of importance. Cognitive recovery was seen as closely tied to context, including the overall life situation and general recovery from ED, which varied between individuals. Hence, different restorative or compensatory strategies were considered helpful, as were optimization of the external environment and a change in approach towards the own self and cognitive performance.

In sum, this thesis studied the subjectively reported cognitive symptoms in ED. It has supported and extended previous findings by showing how substantial cognitive difficulties may be experienced, and that the expression of these problems is intricately linked to different facets and levels of cognition.

Abstract [en]

This thesis aimed to add more empirical knowledge on the self-reported cognitive difficulties experienced by patients diagnosed with stress-related Exhaustion disorder. Using different methods and from different perspectives, it has investigated how questionnaires targeting everyday problems relates to test performance, psychological distress and brain activity. Moreover, qualitative interviews have demonstrated experiences of cognitive functioning 6-10 years after participating in rehabilitation, the course of cognitive problems, and what have been helpful or hindering during the recovery process.

Place, publisher, year, edition, pages
Karlstads universitet, 2025. p. 149
Series
Karlstad University Studies, ISSN 1403-8099 ; 2025:16
Keywords
Exhaustion disorder, Stress, Cognition, Self-report, Subjective cognitive complaints, fMRI, Lived experience, Recovery
National Category
Psychology
Research subject
Psychology
Identifiers
urn:nbn:se:kau:diva-103754 (URN)10.59217/xyim7097 (DOI)978-91-7867-564-7 (ISBN)978-91-7867-565-4 (ISBN)
Public defence
2025-04-29, 11D257, Agardhsalen, 13:00 (Swedish)
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Supervisors
Note

Article 3 part of thesis as manuscript, now published.

Available from: 2025-04-07 Created: 2025-03-28 Last updated: 2025-05-02Bibliographically approved

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