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Laparoscopic Nissen fundoplication is more cost-effective than open Nissen fundoplication in children
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Perinatal, Neonatal and Pediatric Cardiology Research. Uppsala Univ, Akadem Sjukhuset, Sect Pediat Surg, S-75185 Uppsala, Sweden..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Perinatal, Neonatal and Pediatric Cardiology Research.ORCID iD: 0000-0002-5071-3127
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Women's and Children's Health, Perinatal, Neonatal and Pediatric Cardiology Research.
2025 (English)In: Pediatric surgery international (Print), ISSN 0179-0358, E-ISSN 1437-9813, Vol. 41, no 1, article id 66Article in journal (Refereed) Published
Abstract [en]

Background

Nissen fundoplication is one of the most common surgical procedures for gastroesophageal reflux. Current and previous research comparing laparoscopic Nissen fundoplication (LNF) versus open Nissen fundoplication (ONF) in children suggest ambiguous conclusions. The purpose of this retrospective study was to compare the outcome for children operated with LNF or ONF at our institution and to evaluate the economic aspects.

Methods

32 consecutive patients (LNF: n = 18, ONF: n = 14) operated with Nissen fundoplication between the years 2011–2017 were included in the study. Data was collected by examination of the patient journals and preoperative, operative, postoperative, and post-discharge parameters were analyzed.

Results

Compared to ONF, the LNF group had shorter operating time (165.2 vs 216.6 min, p < 0.05), shorter overall operating room duration (315.0 vs 334.9 min, p < 0.05) and shorter postoperative hospital stay (3.8 vs 8.1 days, p < 0.05). The LNF group also required less morphine (1.2 vs 1.7 mg/kg, p < 0.05) and the total cost per case was 39% lower (261.1 vs 427.4 kSEK, p < 0.05). No difference was seen in postoperative complications and results.

Conclusion

Laparoscopic Nissen fundoplication is more cost-effective compared to open surgery and reduces postoperative hospital stay and morphine requirements.

Place, publisher, year, edition, pages
Springer, 2025. Vol. 41, no 1, article id 66
Keywords [en]
Gastroesophageal reflux, GERD, Laparoscopic, Open, Nissen, Fundoplication, Cost
National Category
Surgery
Identifiers
URN: urn:nbn:se:uu:diva-549504DOI: 10.1007/s00383-025-05968-1ISI: 001401110600001PubMedID: 39820516Scopus ID: 2-s2.0-85216043207OAI: oai:DiVA.org:uu-549504DiVA, id: diva2:1939097
Funder
Uppsala UniversityAvailable from: 2025-02-20 Created: 2025-02-20 Last updated: 2025-02-20Bibliographically approved

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Högberg, NiclasDanielson, JohanGustafson, Elisabet
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