This article explores how teachers can support students’ observational drawing skills in the biology classroom. The article is based on classroom data from a collaborative project involving primary school teachers, arts educators, and researchers. Together, we have planned and implemented classroom interventions, aiming to contribute knowledge about the pedagogical potentials of drawing in science. In this article, we analyse one teacher’s way of teaching observational drawing to 8-year-old students. Our analysis reveals two main teaching emphases: (1) the interplay between observing and drawing and (2) the visual characteristics of natural objects, particularly the shape, colour, and specific details of different species. Our findings provide valuable insights for educators who seek to integrate observational drawing into science education. First, we highlight the significance of the teacher’s content knowledge in biology, as it corresponds to the ability to guide students’ attention to specific details in natural objects. Second, we show the pedagogical potential of providing explicit feedback during the drawing process in terms of encouraging students to make detailed and realistic drawings while also making them visually engaging. Lastly, we show that the teacher makes use of verbal, bodily, and visual resources to create a collaborative space for communication around student drawings.