Background: A 25-year-old patient was treated for post-traumatic neck pain with intradiscal injections at the C3-4 and C4-5 levels using radiopaque gelified ethanol. After the injections, the axial neck pain increased. Laboratory infection parameters were normal despite the progressive disc destruction observed on CT scans at both index levels. The patient underwent debridement and anterior cervical discectomy and fusion. Staphylococcus epi-dermidis and Cutibacterium acnes grew in all the intraoperative cultures. The patient was subsequently treated with Rifampicin and Moxifloxacin and after 3 months no signs of infection were observed. CT scan showed solid fusion of the at the index segments 7 months postoperatively.

Conclusion: Infections after intradiscal injections are rare and we believe this is the first case describing iatrogenic spondylodiscitis after DiscoGel injection. When increased axial neck pain is experienced after injection with DiscoGel, post-operative spondylodiscitis should be suspected. Even if laboratory parameters are normal, examinations with MRI and CT should be performed and if these studies show signs of infection, surgical revision should be conducted.