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Acute care bundles should be used for patients with intracerebral haemorrhage: An expert consensus statement
Northern Care Alliance, Manchester Acad Hlth Sci Ctr, Geoffrey Jefferson Brain Res Ctr, Manchester, England.;Univ Manchester, Manchester, England.;Salford Royal Hosp, Stott Lane, Salford M6 8HD, England..ORCID iD: 0000-0002-4462-3846
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Epidemiology. Emergency Department, Uppsala University Hospital, Uppsala, Sweden.
Univ Cincinnati, Coll Med, Dept Emergency Med, Cincinnati, OH USA..
Univ Brescia, Dept Clin & Expt Sci, Neurol Unit, Brescia, Italy..
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2024 (English)In: European Stroke Journal, ISSN 2396-9873, E-ISSN 2396-9881, Vol. 9, no 2, p. 295-302, article id 23969873231220235Article, review/survey (Refereed) Published
Abstract [en]

Purpose:

Intracerebral haemorrhage (ICH) is the most devastating form of stroke and a major cause of disability. Clinical trials of individual therapies have failed to definitively establish a specific beneficial treatment. However, clinical trials of introducing care bundles, with multiple therapies provided in parallel, appear to clearly reduce morbidity and mortality. Currently, not enough patients receive these interventions in the acute phase.

Methods:

We convened an expert group to discuss best practices in ICH and to develop recommendations for bundled care that can be delivered in all settings that treat acute ICH, with a focus on European healthcare systems.

Findings:

In this consensus paper, we argue for widespread implementation of formalised care bundles in ICH, including specific metrics for time to treatment and criteria for the consideration of neurosurgical therapy.

Discussion:

There is an extraordinary opportunity to improve clinical care and clinical outcomes in this devastating disease. Substantial evidence already exists for a range of therapies that can and should be implemented now.

Place, publisher, year, edition, pages
Sage Publications, 2024. Vol. 9, no 2, p. 295-302, article id 23969873231220235
Keywords [en]
Intracerebral haemorrhage, oral anticoagulants, blood pressure, haematoma evacuation, hyperglycaemia, fever, care bundles
National Category
Neurology Neurosciences
Identifiers
URN: urn:nbn:se:uu:diva-549183DOI: 10.1177/23969873231220235ISI: 001131557800001PubMedID: 38149323Scopus ID: 2-s2.0-85180870305OAI: oai:DiVA.org:uu-549183DiVA, id: diva2:1935006
Funder
AstraZenecaNIH (National Institutes of Health), K23HD102555Available from: 2025-02-05 Created: 2025-02-05 Last updated: 2025-02-05Bibliographically approved

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