Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The Tensile Strength of Full-Thickness Skin: A Laboratory Study Prior to Its Use as Reinforcement in Parastomal Hernia Repair
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences. Sunderby Research Unit, Department of Surgical and Perioperative Sciences, Umeå University, Luleå, Sweden.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences.ORCID iD: 0000-0003-1868-292x
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences.
2019 (English)In: Frontiers in Surgery, ISSN 2296-875X, Vol. 6, article id 69Article in journal (Refereed) Published
Abstract [en]

Purpose: Parastomal hernia is a common complication of an enterostoma. Current methods of repair have high recurrence rates and are associated with severe complications. Autologous full-thickness skin as reinforcement may reduce the recurrence and complication rates. This study aims to investigates the tensile strength of full-thickness skin; information that is essential if we are to proceed with clinical trials on humans.

Methods: Full-thickness skin samples from 12 donors were tested for tensile strength, as well as the load tolerated by a suture through the skin. Strips of skin were cut out and stretched until breaking point. Sutures were made through skin samples and traction applied until either the tissue or the suture gave way. All done while recording the forces applied using a dynamometer. Identical tests were carried out on commercially available synthetic and biologic graft material for comparison.

Results: The full-thickness skin strips had a median tensile strength of 604 N/cm. This tensile strength was significantly higher than that of the compared materials evaluated in this study. In full-thickness skin, the suture, or tissue endured a median force of 67 N before giving way, which was as high as, or higher than similar sutures through the compared materials.

Conclusions: The tensile strength of full-thickness skin vastly exceeds the physiological forces affecting the abdominal wall, and sutures through skin endure high loads before giving way. The tensile strength of a full-thickness skin graft and the strength of sutures through this material will not limit its use for reinforcement in parastomal hernia repair.

Place, publisher, year, edition, pages
Frontiers Media S.A., 2019. Vol. 6, article id 69
Keywords [en]
full-thickness skin, tensile strength, parastomal hernia, composite mesh, biological mesh
National Category
Surgery
Identifiers
URN: urn:nbn:se:umu:diva-167058DOI: 10.3389/fsurg.2019.00069ISI: 000503267800001OAI: oai:DiVA.org:umu-167058DiVA, id: diva2:1383986
Funder
Västerbotten County CouncilSwedish Research Council, 2017: 950 834Available from: 2020-01-09 Created: 2020-01-09 Last updated: 2020-01-09Bibliographically approved

Open Access in DiVA

fulltext(522 kB)3 downloads
File information
File name FULLTEXT01.pdfFile size 522 kBChecksum SHA-512
fba386daecf25f9054a3ee54413bce25f90fc84863ae9d92ecae67b10d72494f841c00b9096d25929f9d65e8896ccf8fa2653ba17ef2233189167f8c2cf849ec
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Holmdahl, ViktorBackman, OlofGunnarsson, UlfStrigård, Karin
By organisation
Department of Surgical and Perioperative Sciences
Surgery

Search outside of DiVA

GoogleGoogle Scholar
Total: 3 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 4 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf