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Long distance ski racing is associated with lower long-term incidence of depression in a population based, large-scale study
Lund Univ, Dept Expt Med Sci, Expt Neuroinfiammat Lab, BMC B11, S-22184 Lund, Sweden.
Van Andel Res Inst, Ctr Neurodegenerat Sci, Grand Rapids, MI USA.ORCID iD: 0000-0002-8327-6242
Karolinska Inst, Dept Physiol & Pharmacol, Stockholm, Sweden.
Van Andel Res Inst, Ctr Neurodegenerat Sci, Grand Rapids, MI USA.
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2019 (English)In: Psychiatry Research, ISSN 0165-1781, E-ISSN 1872-7123, Vol. 281, article id 112546Article in journal (Refereed) Published
Abstract [en]

Physical activity has been proposed to be beneficial for prevention of depression, although the importance of exercise intensity, sex-specific mechanisms, and duration of the effects need to be clarified. Using an observational study design, following 395,369 individuals up to 21 years we studied whether participation in an ultralong-distance cross-country ski race was associated with lower risk of developing depression. Skiers (participants in the race) and matched non-skiers from the general population (non-participants in the race) were studied after participation (same year for non-participation) in the race using the Swedish population and patient registries. The risk of depression in skiers (n = 197,685, median age 36 years, 38% women) was significantly lower, to nearly half of that in non-skiers (adjusted hazard ratio, HR 0.53) over the follow-up period. Further, a higher fitness level (measured as the finishing time to complete the race, a proxy for higher exercise dose) was associated with lower incidence of depression in men (adjusted HR 0.65), but not in women. Our results support the recommendations of engaging in physical activity as a preventive strategy decreasing the risk for depression in both men and women. Furthermore, the exercise could reduce risk for depression in a dose-dependent matter, in particular in males.

Place, publisher, year, edition, pages
ELSEVIER IRELAND LTD , 2019. Vol. 281, article id 112546
Keywords [en]
Exercise, Psychiatric disorder, Mental health, Women, Men, Long-term effect
National Category
Cardiac and Cardiovascular Systems Sport and Fitness Sciences
Identifiers
URN: urn:nbn:se:uu:diva-400098DOI: 10.1016/j.psychres.2019.112546ISI: 000497252200017PubMedID: 31622872OAI: oai:DiVA.org:uu-400098DiVA, id: diva2:1383109
Funder
Swedish Research CouncilThe Swedish Brain FoundationMultidisciplinary research focused on Parkinson’s disease - MultiParkStiftelsen Olle Engkvist ByggmästareThe Dementia Association - The National Association for the Rights of the DementedSwedish Research Council, 2017-00875Available from: 2020-01-07 Created: 2020-01-07 Last updated: 2020-01-08Bibliographically approved

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