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From IBS to DBS: The Dysbiotic Bowel Syndrome
Lakarhuset Hotorgsc, Stockholm, Sweden;Karolinska Inst, Stockholm, Sweden.
Karolinska Inst, Stockholm, Sweden.
Lakarhuset Hotorgsc, Stockholm, Sweden.
Karolinska Inst, Stockholm, Sweden.
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2016 (English)In: JOURNAL OF INVESTIGATIVE MEDICINE HIGH IMPACT CASE REPORTS, ISSN 2324-7096, Vol. 4, no 2, article id UNSP 2324709616648458Article in journal (Refereed) Published
Abstract [en]

Irritable bowel syndrome is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits in the absence of organic disease. We present 2 cases where diarrhea-predominant irritable bowel syndrome occurred in association with earlier intestinal infection or antibiotic treatment. Both were successfully treated with instillation of an anaerobic cultivated human intestinal microbiota. Thereafter, they were symptom free for at least 12 months. We now introduce the term dysbiotic bowel syndrome covering cases where a disturbed intestinal microbiota is assumed to be present. We recommend that restoration of the dysbiotic gut microbiota should be first-line treatment in these conditions.

Place, publisher, year, edition, pages
SAGE PUBLICATIONS LTD , 2016. Vol. 4, no 2, article id UNSP 2324709616648458
Keywords [en]
irritable bowel syndrome, microbiota, postinfectious IBS, diarrhea, pain, dysbiosis
National Category
Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:uu:diva-400806DOI: 10.1177/2324709616648458ISI: 000457921000012PubMedID: 27231695OAI: oai:DiVA.org:uu-400806DiVA, id: diva2:1382569
Available from: 2020-01-03 Created: 2020-01-03 Last updated: 2020-01-03Bibliographically approved

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