Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
En jämförelse av effekten hos protonpumpshämmare och histamin-2-receptorantagonister vid behandling av NSAID-associerade magsår
Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
2019 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [sv]

Icke-steroida antiinflammatoriska läkemedel (NSAID) är ett samlingsnamn för olika antipyretiska, analgetiska och antiinflammatoriska läkemedel och är bland de mest använda läkemedlen i världen. Dock kan användning av NSAID leda till magsår. I denna litteraturstudie undersöks effekten av PPI respektive H2RA vid behandling och förebyggande av NSAID-inducerat magsår. Med hjälp av databasen PubMed valdes fem kliniska studier ut. De rapporterade resultaten analyserades noga och sammanställdes. Resultatet i de olika studierna tyder på att PPI är 5 till 15 % mer effektiv än H2RA med avseende på effekt vid behandling av NSAID-inducerat magsår och att PPI är 10 % mer effektiv än H2RA med avseende på effekt vid förebyggandet av NSAID-inducerat magsår.

Abstract [en]

Non-steroidal anti-inflammatory drug (NSAID) is a collective name for various antipyretic, analgesic and anti-inflammatory drugs and are among the most used drugs in the world. However, the use of NSAIDs can lead to gastric ulcers. In this literature study, the effects of PPI and H2RA, respectively, in the treatment and prevention of NSAID-induced gastric ulcer are studied. Five clinical studies were selected using the PubMed database. The reported results were carefully analyzed and compiled. The results in the different studies indicate that PPI is 5 to 15% more effective than H2RA in terms of efficacy in the treatment of NSAID-induced gastric ulcer and that PPI is 10% more effective than H2RA in terms of efficacy in the prevention of NSAID-induced gastric ulcer.

Place, publisher, year, edition, pages
2019. , p. 30
Keywords [sv]
NSAID, protonpumpshämmare, histamin-2-receptorantagonist, magsår.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:lnu:diva-90337OAI: oai:DiVA.org:lnu-90337DiVA, id: diva2:1374371
Subject / course
Pharmacy
Educational program
Bachelor of Science Programme in Pharmacy, 180 credits
Supervisors
Examiners
Available from: 2019-12-02 Created: 2019-11-29 Last updated: 2019-12-02Bibliographically approved

Open Access in DiVA

fulltext(382 kB)1 downloads
File information
File name FULLTEXT01.pdfFile size 382 kBChecksum SHA-512
087ed5d1c3f9b6803c0016bf7807a8c1d19a43f6ccd9969662c2a428e2ad87793230d11e5283a05d424e836e4774e1eecc11f5329e7de6226b73c81a8d9ac273
Type fulltextMimetype application/pdf

Search in DiVA

By author/editor
El Saleh, Iman
By organisation
Department of Chemistry and Biomedical Sciences
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 1 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

urn-nbn

Altmetric score

urn-nbn
Total: 13 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf