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Burst Spinal Cord Stimulation: A Clinical Review
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Anaesthesiology and Intensive Care.
Krankenhaus Neuwerk Maria Aposteln Muskuloskeleta, Dept Intervent Schmerzmed, Monchengladbach, Germany.
Diakonessenhuis Utrecht, Dept Anesthesiol & Pain Management, Utrecht, Netherlands.
Ainsworth Inst Pain Management, New York, NY USA.
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2019 (English)In: Pain medicine (Malden, Mass.), ISSN 1526-2375, E-ISSN 1526-4637, Vol. 20, p. S31-S40Article, review/survey (Refereed) Published
Abstract [en]

Objective

Clinical review on outcomes using burst spinal cord stimulation (SCS) in the treatment of chronic, intractable pain.

Design

Narrative clinical literature review conducted utilizing a priori search terms including key words for burst spinal cord stimulation. Synthesis and reporting of data from publications including an overview of comparative SCS outcomes.

Results

Burst SCS demonstrated greater pain relief over tonic stimulation in multiple studies, which included blinded, sham-controlled, randomized trials. Additionally, burst stimulation impacts multiple dimensions of pain, including somatic pain as well as emotional and psychological elements. Patient preference is weighted toward burst over tonic due to increased pain relief, a lack of paresthesias, and impression of change in condition.

Conclusion

Burst SCS has been shown to be both statistically and clinically superior to tonic stimulation and may provide additional benefits through different mechanisms of action. Further high-quality controlled studies are warranted to not only elucidate the basic mechanisms of burst SCS but also address how this unique stimulation signature/pattern may more adequately handle the multiple affective dimensions of pain in varying patient populations.

Place, publisher, year, edition, pages
2019. Vol. 20, p. S31-S40
Keywords [en]
Burst, Spinal Cord Stimulation, Outcomes, Clinical
National Category
Neurology
Identifiers
URN: urn:nbn:se:uu:diva-395638DOI: 10.1093/pm/pnz003ISI: 000486254400005PubMedID: 31152175OAI: oai:DiVA.org:uu-395638DiVA, id: diva2:1364971
Note

Terje Kirketeig, Carsten Schultheis and Xander Zuidema contributed equally.

Available from: 2019-10-23 Created: 2019-10-23 Last updated: 2019-10-23Bibliographically approved

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