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Patch Testing with a New Composition of Mercapto Mix: A Multi-centre Study by the Swedish Contact Dermatitis Research Group
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Dermatology and Venerology.
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2019 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 99, no 11, p. 960-963Article in journal (Refereed) Published
Abstract [en]

This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch-tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0-0.50%, 0-0.93%, and 0-1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The authors recommend replacing mercapto mix 2.0% pet. in the Swedish baseline series with mercapto mix 3.5% pet., since the latter also detected those patients who would have been missed because MBT 2.0% is not included in the Swedish baseline series.

Place, publisher, year, edition, pages
Acta Dermato-Venereologica , 2019. Vol. 99, no 11, p. 960-963
Keywords [en]
allergic contact dermatitis, contact allergy, 2-mercaptobenzothiazole, mercapto mix, rubber, delayed hypersensitivity
National Category
Dermatology and Venereal Diseases
Identifiers
URN: urn:nbn:se:umu:diva-164037DOI: 10.2340/00015555-3249ISI: 000487762500003PubMedID: 31240321OAI: oai:DiVA.org:umu-164037DiVA, id: diva2:1361566
Available from: 2019-10-16 Created: 2019-10-16 Last updated: 2019-10-16Bibliographically approved

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