To achieve effective regulation, the OECD and the European Commission recommend the use of regulatory impact assessment (RIA). The full RIA process has however not been implemented in Sweden. There is for example a lack of established practices at the national level for the analysis of risk in regulatory work. Instead, soft law in the form of management by objective systems is guiding transport and environmental policy. These systems were introduced in the end of the 1990s following the international discussion on the precautionary principle. According to findings in other countries, policy making based on the precautionary principle may result in unexpected and unwanted consequences and therefore, based on a literature review and an assessment of current practices in transport regulation in Sweden, we suggest the use of an initial screening of hazards in regulatory work. We also apply the proposed method to four transport related case studies to illustrate how an initial assessment can provide the basis for an informed discussion on what hazards to counteract with regulation and on what grounds.