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Infantile tremor syndrome: current perspectives
Govt Med Coll, Dept Paediat, Datia, MP, India.
Bundelkhand Med Coll, Dept Paediat, Sagar, MP, India.
All India Inst Med Sci, Dept Neonatol, Rishikesh, Uttarakhand, India.
Chirayu Med Coll, Dept Microbiol, Bhopal, MP, India.
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2019 (English)In: Research and Reports in Tropical Medicine, ISSN 1179-7282, Vol. 10, p. 103-108Article, review/survey (Refereed) Published
Abstract [en]

Infantile Tremor Syndrome (ITS) is a self-limiting clinical state characterized by tremors, anemia, pigmentary skin disease, regression of mental development, and hypotonia of muscles in a plump looking child. Tremors are coarse in character, decreased or disappeared in sleep and resolves within 4-6 weeks in its natural course. Various etiological factors as infectious, metabolic, nutritional have been hypothesized but none is conclusive. Consensus is developing on the role of Vitamin B12 deficiency in children with ITS but is still debatable. Empirical management of ITS children has been tried in the absence of exact etiology considering child as undernourished. Nutritional management includes supplementation of Iron, Calcium, Magnesium, Vitamin B12 and other multivitamins. Tremors can be managed with administration of propranolol most commonly or phenobarbitone, phenytoin, and carbamazepine.

Place, publisher, year, edition, pages
DOVE MEDICAL PRESS LTD , 2019. Vol. 10, p. 103-108
Keywords [en]
tremors, infantile tremor syndrome, undernutrition, vitamin B12
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:uu:diva-391435DOI: 10.2147/RRTM.S180604ISI: 000476598200001PubMedID: 31308787OAI: oai:DiVA.org:uu-391435DiVA, id: diva2:1354651
Available from: 2019-09-25 Created: 2019-09-25 Last updated: 2019-09-25Bibliographically approved

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