Sequential Monte Carlo (SMC) methods comprise one of the most successful approaches to approximate Bayesian filtering. However, SMC without a good proposal distribution can perform poorly, in particular in high dimensions. We propose nested sequential Monte Carlo, a methodology that generalizes the SMC framework by requiring only approximate, properly weighted, samples from the SMC proposal distribution, while still resulting in a correctSMCalgorithm. This way, we can compute an "exact approximation" of, e. g., the locally optimal proposal, and extend the class of models forwhichwe can perform efficient inference using SMC. We showimproved accuracy over other state-of-the-art methods on several spatio-temporal state-space models.