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Resistance training for hot flushes in postmenopausal women: A randomised controlled trial
Linköping University, Department of Clinical and Experimental Medicine, Division of Children's and Women's health. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Primary Care Center, Primary Health Care Center Nygatan, Linköping.
Linköping University, Department of Clinical and Experimental Medicine, Division of Children's and Women's health. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.
Linköping University, Department of Medical and Health Sciences, Division of Physiotherapy. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.ORCID iD: 0000-0002-1533-6872
Linköping University, Department of Clinical and Experimental Medicine, Division of Children's and Women's health. Linköping University, Faculty of Medicine and Health Sciences. Region Östergötland, Center of Paediatrics and Gynaecology and Obstetrics, Department of Gynaecology and Obstetrics in Linköping.
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2019 (English)In: Maturitas, ISSN 0378-5122, E-ISSN 1873-4111, Vol. 126, p. 55-60Article in journal (Refereed) Published
Abstract [en]

Objectives: To investigate the effect of 15 weeks of resistance training on the frequency of moderate to severe hot flushes in postmenopausal women. Study design: Postmenopausal women with at least 4 moderate or severe hot flushes or night sweats per day day were randomized to a 15-week resistance training intervention or unchanged physical activity. Participants did not exercise regularly at baseline and had not used any therapy for hot flushes two months prior to study entry. The resistance training was performed three times per week and the program contained 8 exercises performed with 8-12 repetitions in 2 sets. Loads were set individually from eight-repetition maximum-strength tests and increased progressively. Main outcome measures: The primary outcome was change in mean moderate or severe hot flushes per day from baseline to week 15, assessed with symptom diaries. Secondary outcomes included change in hot flush score and time spent on physical activity. Results: Between November 19, 2013, and October 26, 2016, 65 women were enrolled; 58 completed the trial and were included in the analyses. The mean age was 55 and the mean number of moderate or severe hot flushes per day at baseline was 7.1; there were no baseline differences between groups. The frequency of hot flushes decreased more in the intervention group than in the control group (mean difference -2.7, 95% CI -4.2 to -1.3). The mean percentage change was -43.6% (-56.0 to -31.3) in the intervention group and -2.0% (16.4-12.4) in the control group. Conclusion: A 15-week resistance-training program decreased the frequency of moderate and severe hot flushes among postmenopausal women and could be an effective and safe treatment option to alleviate vasomotor symptoms.

Place, publisher, year, edition, pages
ELSEVIER IRELAND LTD , 2019. Vol. 126, p. 55-60
Keywords [en]
Hot flashes; Menopause; Resistance training; Women; Exercise; Randomised controlled trial
National Category
Obstetrics, Gynecology and Reproductive Medicine
Identifiers
URN: urn:nbn:se:liu:diva-159240DOI: 10.1016/j.maturitas.2019.05.005ISI: 000475721400010PubMedID: 31239119OAI: oai:DiVA.org:liu-159240DiVA, id: diva2:1341281
Note

Funding Agencies|Swedish Research Council [2014-2781]; Ministry of Education and Research

Available from: 2019-08-08 Created: 2019-08-08 Last updated: 2019-11-15

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Berin, EmiliaHammar, MatsLindblom, HannaLindh Åstrand, LottaRubér, MarieSpetz Holm, Anna-Clara
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Division of Children's and Women's healthFaculty of Medicine and Health SciencesPrimary Health Care Center Nygatan, LinköpingDepartment of Gynaecology and Obstetrics in LinköpingDivision of Physiotherapy
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