Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The horse Y chromosome as an informative marker for tracing sire lines
Univ Vet Med Vienna, Inst Anim Breeding & Genet, A-1210 Vienna, Austria;Vienna Grad Sch Populat Genet, Vienna, Austria.
Univ Vet Med Vienna, Inst Anim Breeding & Genet, A-1210 Vienna, Austria.
Univ Vet Med Vienna, Inst Anim Breeding & Genet, A-1210 Vienna, Austria.
Univ Vet Med Vienna, Inst Anim Breeding & Genet, A-1210 Vienna, Austria.
Show others and affiliations
2019 (English)In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 9, article id 6095Article in journal (Refereed) Published
Abstract [en]

Analysis of the Y chromosome is the best-established way to reconstruct paternal family history in humans. Here, we applied fine-scaled Y-chromosomal haplotyping in horses with biallelic markers and demonstrate the potential of our approach to address the ancestry of sire lines. We de novo assembled a draft reference of the male-specific region of the Y chromosome from Illumina short reads and then screened 5.8 million basepairs for variants in 130 specimens from intensively selected and rural breeds and nine Przewalski's horses. Among domestic horses we confirmed the predominance of a young'crown haplogroup' in Central European and North American breeds. Within the crown, we distinguished 58 haplotypes based on 211 variants, forming three major haplogroups. In addition to two previously characterised haplogroups, one observed in Arabian/Coldblooded and the other in Turkoman/Thoroughbred horses, we uncovered a third haplogroup containing Iberian lines and a North African Barb Horse. In a genealogical showcase, we distinguished the patrilines of the three English Thoroughbred founder stallions and resolved a historic controversy over the parentage of the horse 'Galopin', born in 1872. We observed two nearly instantaneous radiations in the history of Central and Northern European Y-chromosomal lineages that both occurred after domestication 5,500 years ago.

Place, publisher, year, edition, pages
2019. Vol. 9, article id 6095
National Category
Genetics and Breeding in Agricultural Sciences
Identifiers
URN: urn:nbn:se:uu:diva-382849DOI: 10.1038/s41598-019-42640-wISI: 000464495800019PubMedID: 30988347OAI: oai:DiVA.org:uu-382849DiVA, id: diva2:1317399
Available from: 2019-05-22 Created: 2019-05-22 Last updated: 2019-05-22Bibliographically approved

Open Access in DiVA

fulltext(2961 kB)39 downloads
File information
File name FULLTEXT01.pdfFile size 2961 kBChecksum SHA-512
b5cfc33ed4b0ad3425cdb6f6026c4a229b3bb53a0ca263aa3b63310c1b76c89a4a13834438e654d5b53ac3469406df07f18ef31ea2132a4746f93bc58aec8773
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Rubin, Carl-Johan
By organisation
Department of Medical Biochemistry and MicrobiologyScience for Life Laboratory, SciLifeLab
In the same journal
Scientific Reports
Genetics and Breeding in Agricultural Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 39 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 194 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf