Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Liver fat: a relevant target for dietary intervention? Summary of a Unilever workshop
Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands.
Maastricht Univ, Med Ctr, NUTRIM Sch Nutr & Translat Res Metab, Dept Human Biol, Maastricht, Netherlands.
Unilever Res Labs, Olivier van Noortlaan 120, Vlaardingen, Netherlands.
Univ Southampton, Fac Med, Nutr & Metab, Southampton, Hants, England;Univ Hosp Southampton, Southampton Natl Inst Hlth Res, Biomed Res Ctr, Southampton, Hants, England.ORCID iD: 0000-0001-6322-7753
Show others and affiliations
2017 (English)In: Journal of Nutritional Science, ISSN 2048-6790, E-ISSN 2048-6790, Vol. 6, article id e15Article, review/survey (Refereed) Published
Abstract [en]

Currently it is estimated that about 1 billion people globally have non-alcoholic fatty liver disease (NAFLD), a condition in which liver fat exceeds 5 % of liver weight in the absence of significant alcohol intake. Due to the central role of the liver in metabolism, the prevalence of NAFLD is increasing in parallel with the prevalence of obesity, insulin resistance and other risk factors of metabolic diseases. However, the contribution of liver fat to the risk of type 2 diabetes mellitus and CVD, relative to other ectopic fat depots and to other risk markers, is unclear. Various studies have suggested that the accumulation of liver fat can be reduced or prevented via dietary changes. However, the amount of liver fat reduction that would be physiologically relevant, and the timeframes and dose-effect relationships for achieving this through different diet-based approaches, are unclear. Also, it is still uncertain whether the changes in liver fat per se or the associated metabolic changes are relevant. Furthermore, the methods available to measure liver fat, or even individual fatty acids, differ in sensitivity and reliability. The present report summarises key messages of presentations from different experts and related discussions from a workshop intended to capture current views and research gaps relating to the points above.

Place, publisher, year, edition, pages
CAMBRIDGE UNIV PRESS , 2017. Vol. 6, article id e15
Keywords [en]
Liver fat, Diet, Type 2 diabetes, Cardiovascular disease
National Category
Endocrinology and Diabetes Gastroenterology and Hepatology
Identifiers
URN: urn:nbn:se:uu:diva-377427DOI: 10.1017/jns.2017.13ISI: 000400857100001PubMedID: 28630692OAI: oai:DiVA.org:uu-377427DiVA, id: diva2:1290078
Available from: 2019-02-19 Created: 2019-02-19 Last updated: 2019-02-19Bibliographically approved

Open Access in DiVA

fulltext(430 kB)48 downloads
File information
File name FULLTEXT01.pdfFile size 430 kBChecksum SHA-512
9171c72738fcce189bbcd1f41e68d05b957d743dc9d1b8245b6e02ba3fe8545f5dcbc0d1eff861194186251fe251b5bcaa55b3d6fc96079e71ca95de93b77ed0
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Byrne, Christopher D.Pfeiffer, Andreas F. H.Risérus, Ulf
By organisation
Clinical Nutrition and Metabolism
In the same journal
Journal of Nutritional Science
Endocrinology and DiabetesGastroenterology and Hepatology

Search outside of DiVA

GoogleGoogle Scholar
Total: 48 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 41 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf