Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Cross-sectional and longitudinal analyses of the association between lung function and exercise capacity in healthy Norwegian men
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Clinical Physiology.ORCID iD: 0000-0002-5970-5836
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.ORCID iD: 0000-0001-5093-6980
Show others and affiliations
2018 (English)In: BMC Pulmonary Medicine, ISSN 1471-2466, E-ISSN 1471-2466Article in journal (Refereed) Published
Abstract [en]

BACKGROUND:

It is widely accepted that exercise capacity in healthy individuals is limited by the cardiac function, while the respiratory system is considered oversized. Although there is physiological, age-related decline in both lung function and physical capacity, the association between decline in lung function and decline in exercise capacity is little studied. Therefore, we examined the longitudinal association between lung function indices and exercise capacity, assessed by the total amount of work performed on a standardized incremental test, in a cohort of middle-aged men.

METHODS:

A total of 745 men between 40 and 59 years were examined using spirometry and standardized bicycle exercise ECG test within "The Oslo Ischemia Study," at two time points: once during 1972-1975, and again, approximately 16 years later, during 1989-1990. The subjects exercise capacity was assessed as physical fitness i.e. the total bicycle work (in Joules) at all workloads divided by bodyweight (in kg).

RESULTS:

Higher FEV1, FVC and PEF values related to higher physical fitness at both baseline and follow-up (all p values < 0.05). Higher explanatory values were found at follow-up than baseline for FEV1 (r2 = 0.16 vs. r2 = 0.03), FVC (r2 = 0.14 vs. r2 = 0.03) and PEF (r2 = 0.13 vs. r2 = 0.02). No significant correlations were found between decline in physical fitness and declines in FEV1, FVC or PEF.

CONCLUSIONS:

A weak association between lung function indices and exercise capacity, assessed through physical fitness, was found in middle-aged, healthy men. This association was strengthened with increasing age, suggesting a larger role for lung function in limiting exercise capacity among elderly subjects. However, decline in physical fitness over time was not related to decline in lung function.

Place, publisher, year, edition, pages
2018.
National Category
Respiratory Medicine and Allergy
Research subject
Clinical Physiology
Identifiers
URN: urn:nbn:se:uu:diva-356371DOI: 10.1186/s12890-018-0655-z.OAI: oai:DiVA.org:uu-356371DiVA, id: diva2:1235250
Available from: 2018-07-24 Created: 2018-07-24 Last updated: 2018-07-31Bibliographically approved

Open Access in DiVA

fulltext(584 kB)1 downloads
File information
File name FULLTEXT01.pdfFile size 584 kBChecksum SHA-512
4b1e6c716caa865f500333812ea91054c993354590b04c19a620cd3513120075b571e35a68d7a1a84b110c5be821b749cff314c42a39e0e1eb34f6aac312b74a
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Farkhooy, AmirJanson, ChristerHedenström, HansMalinovschi, Andrei
By organisation
Clinical PhysiologyLung- allergy- and sleep research
In the same journal
BMC Pulmonary Medicine
Respiratory Medicine and Allergy

Search outside of DiVA

GoogleGoogle Scholar
Total: 1 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 4 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf