Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Validering av S-Zink på Beckman Coulter AU680: samt hållbarhetsstudie och provrörsstudie
Linnaeus University, Faculty of Health and Life Sciences, Department of Chemistry and Biomedical Sciences.
2018 (Swedish)Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Zinc is an essential mineral that has many biological and structural functions in the cells. In Sweden, zinc analysis is performed with different methods and test tubes. The recommended value of zinc is between 11-17 µmol/L together with normal albumin rate. The aim of this study was to validate the colorimetric method for analysis of S-Zinc by comparing the results from two Beckman Coulter AU680 instruments for the insertion of these at the Department of Clinical Chemistry and Transfusion Medicine, Country council of Kalmar. Precision study, correlation study and comparison study was made between the kinds of test tubes BD Vacutainer® Blood Collection Tubes, one consisting of a gel separator, one without contents and the last type contained silica particles. A correlation study was made by comparing patient samples obtained from the department of clinical chemistry, Country council of Jönköping. In the comparison study, serum probes were provided by the staff at the Department of Clinical Chemistry, Kalmar. The blood samples were taken in two kinds of blood collection tubes without contents (one containing silica particles) and one blood collection tubes with gel. The serum tests were analyzed for 4 days and the test results were studied and compared between the collection types. The conclusion of the study was that S-Zink on the Beckman Coulter AU680 instrument with reagents from Sentinel Diagnostic was acceptable. Both Beckman Coulter AU680 instruments provided equivalent results. The correlation between Beckman Coulter AU680 and Thermo Konelab Prime 30i was acceptable. The correlation coefficient showed a high correlation rate between the different methods (r=0, 93). The sustainability of the serum samples, that was poured in new tubes and stored in 2-8°C for 4 days, was good. The study showed distinct differences when analyzing different blood collection tubes, were the collection tube containing gel showed a higher zinc rate. When insertion of the new method, S-Zink, it is recommended that blood collection tubes without contents are used, because of the risk of zinc contamination from collection tubes with gel and plastic stoppers.

Place, publisher, year, edition, pages
2018. , p. 23
Keywords [sv]
Zinkanalys. Validering. Beckman Coulter AU680.
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:lnu:diva-76650OAI: oai:DiVA.org:lnu-76650DiVA, id: diva2:1230755
Subject / course
Biomedical Laboratory Science
Educational program
Biomedical Laboratory Science Programme, 180 credits
Supervisors
Examiners
Available from: 2018-07-04 Created: 2018-07-04 Last updated: 2018-07-04Bibliographically approved

Open Access in DiVA

fulltext(1035 kB)8 downloads
File information
File name FULLTEXT01.pdfFile size 1035 kBChecksum SHA-512
ba7a3e91007b6b985d6d57bf2c67ea95ac4ab7b7ab962d4df23d9de35108bfbd00d209ccb3d424c84fc117bdb8584a17032ab7dc8ac5913166606ec5f76d80e6
Type fulltextMimetype application/pdf

By organisation
Department of Chemistry and Biomedical Sciences
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 8 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

urn-nbn

Altmetric score

urn-nbn
Total: 26 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf