Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Prevalence of asthma-like symptoms with ageing
Imperial Coll, Natl Heart & Lung Inst, Populat Hlth & Occupat Dis, Emmanuel Kaye Bldg, London SW3 6LR, England.;Imperial Coll London, PHE Ctr Environm & Hlth, MRC, London, England..
Imperial Coll London, Dept Primary Care & Publ Hlth, London, England..
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Sciences, Lung- allergy- and sleep research.
Univ Pavia, Div Resp Dis, Dept Internal Med & Therapeut, IRCCS,Policlin San Matteo Fdn, Pavia, Italy..
Show others and affiliations
2018 (English)In: Thorax, ISSN 0040-6376, E-ISSN 1468-3296, Vol. 73, no 1, p. 37-48Article in journal (Refereed) Published
Abstract [en]

Background: Change in the prevalence of asthma-like symptoms in populations of ageing adults is likely to be influenced by smoking, asthma treatment and atopy.

Methods: The European Community Respiratory Health Survey collected information on prevalent asthma-like symptoms from representative samples of adults aged 20–44 years (29 centres in 13 European countries and Australia) at baseline and 10 and 20 years later (n=7844). Net changes in symptom prevalence were determined using generalised estimating equations (accounting for non-response through inverse probability weighting), followed by meta-analysis of centre level estimates.

Findings: Over 20 years the prevalence of ‘wheeze’ and ‘wheeze in the absence of a cold’ decreased (−2.4%, 95% CI −3.5 to −1.3%; −1.5%, 95% CI −2.4 to −0.6%, respectively) but the prevalence of asthma attacks, use of asthma medication and hay fever/nasal allergies increased (0.6%, 95% CI 0.1 to 1.11; 3.6%, 95% CI 3.0 to 4.2; 2.7%, 95% CI 1.7 to 3.7). Changes were similar in the first 10 years compared with the second 10 years, except for hay fever/nasal allergies (increase seen in the first 10 years only). Decreases in these wheeze-related symptoms were largely seen in the group who gave up smoking, and were seen in those who reported hay fever/nasal allergies at baseline.

Interpretation: European adults born between 1946 and 1970 have, over the last 20 years, experienced less wheeze, although they were more likely to report asthma attacks, use of asthma medication and hay fever. Decrease in wheeze is largely attributable to smoking cessation, rather than improved treatment of asthma. It may also be influenced by reductions in atopy with ageing.

Place, publisher, year, edition, pages
2018. Vol. 73, no 1, p. 37-48
National Category
Respiratory Medicine and Allergy
Identifiers
URN: urn:nbn:se:uu:diva-339760DOI: 10.1136/thoraxjnl-2016-209596ISI: 000417923500009PubMedID: 28974648OAI: oai:DiVA.org:uu-339760DiVA, id: diva2:1179741
Funder
Swedish Asthma and Allergy AssociationSwedish Heart Lung FoundationCancer and Allergy FoundationForte, Swedish Research Council for Health, Working Life and WelfareAvailable from: 2018-02-02 Created: 2018-02-02 Last updated: 2018-02-02Bibliographically approved

Open Access in DiVA

fulltext(1415 kB)6 downloads
File information
File name FULLTEXT01.pdfFile size 1415 kBChecksum SHA-512
d74ad7e60abe90b409e4724c6072603d6f5bc2d61ab3033b8ed93f30c1ab7aaacbcdeba25d3b2c8e71510378aa1d6fbe5bf3c82d8f5aca4f8c58b6851a183be7
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Janson, ChristerSvanes, Cecilie
By organisation
Lung- allergy- and sleep research
In the same journal
Thorax
Respiratory Medicine and Allergy

Search outside of DiVA

GoogleGoogle Scholar
Total: 6 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 30 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf