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Ett nytt semantiskt intraoperativt test på svenska: Baserat på DuLIP:s semantic odd word out
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Logopedi.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Neuroscience, Logopedi.
2018 (Swedish)Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Low-grade gliomas (LGGs) constitute a major challenge for health care because of their location and nature. LGGs are often found in eloquent areas, and their infiltrative growth cause neurological reorganization, which complicates the mapping of important functions. Awake surgery in combination with direct electrical stimulation (DES) and intraoperative tests is a relatively new method for mapping the brain's functional limits, thus eliminating as much of the tumor as possible while maintaining important functions. At present there is no available intraoperative test for semantic processing in Swedish. Tests of specific linguistic abilities improves the specificity of mapping which reduces post-operative linguistic impairments. Intraoperative tests can thus contribute to increased quality of life in the patient group. This study was based on the Dutch Lingusistic Intraoperative Protocol (DuLIP) test battery to create a Swedish version of the subtest semantic odd word out (SOWO). SOWO tests semantic processing via lexical reading. The adjusted and extended version of SOWO was tested during a pilot trial on 26 standard-language people. The study has resulted in a new semantic intraoperative test in Swedish that will be clinically examined at University Hospital in Uppsala. Hopefully, the new test contributes to better treatment options for patients with LGG.

Abstract [sv]

Lågmaligna tumörer (LGG) utgör en stor utmaning för vården på grund av deras lokalisation och karaktär. LGG återfinns ofta i elokventa områden och deras infiltrativa växtsätt orsakar neurologisk omorganisering, vilket komplicerar kartläggning av viktiga funktioner. Vakenkirurgi i kombination med direkt elektrisk stimulering (DES) och intraoperativa tester är en relativt ny metod för att kartlägga hjärnans funktionella gränser och därmed kunna avlägsna så stor del av tumören som möjligt samtidigt som viktiga funktioner kan bevaras. I dagsläget finns det inget tillgängligt intraoperativt test för semantisk bearbetning på svenska. Tester av specifika lingvistiska förmågor förbättrar specificiteten av kartläggningen vilket minskar postoperativa språkliga nedsättningar. Intraoperativa tester kan därmed bidra till ökad livskvalitet hos patientgruppen. Denna studie har utgått från det nederländska testbatteriet Dutch Lingusistic Intraoperative Protocol (DuLIP) för att skapa en svensk version av deltestet semantic odd word out (SOWO). SOWO testar semantisk bearbetning via lexikal läsning. Den anpassade och utökade versionen av SOWO pilottestades på 26 normalspråkiga personer. Studien har resulterat i ett nytt semantiskt intraoperativt test på svenska som ska prövas kliniskt på Akademiska sjukhuset i Uppsala. Förhoppningsvis bidrar det nya testet till bättre behandlingsmöjligheter för patienter med LGG.

Place, publisher, year, edition, pages
2018. , p. 64
Series
Magisterarbete i logopedi ; 151
Keywords [en]
Low-grade glioma, awake surgery, intraoperative language test, DuLIP, semantics, lexical reading, subcortical pathways, speech and language pathology
Keywords [sv]
Lågmaligna gliom, vakenkirurgi, intraoperativa språktest, DuLIP, semantik, lexikal läsning, subkortikala banor, logopedi
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-338661OAI: oai:DiVA.org:uu-338661DiVA, id: diva2:1173022
Subject / course
Speech and Language Pathology
Educational program
Degree of Master of Science in Speech and Language Pathology
Supervisors
Examiners
Available from: 2018-01-12 Created: 2018-01-11 Last updated: 2018-01-12Bibliographically approved

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