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Change in Use of Sleep Medications After Gastric Bypass Surgery or Intensive Lifestyle Treatment in Adults with Obesity
Karolinska Inst, Dept Med, Solna, Clin Epidemiol Unit, Stockholm, Sweden.;Baker Heart & Diabet Inst, Clin Diabet & Epidemiol, Melbourne, Vic, Australia.;Deakin Univ, Fac Hlth, Sch Hlth & Social Dev, Geelong, Vic, Australia.;Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia..
Deakin Univ, Fac Hlth, Sch Hlth & Social Dev, Geelong, Vic, Australia.;Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia..
Univ Orebro, Fac Med & Hlth, Dept Surg, Orebro, Sweden..
Univ Orebro, Fac Med & Hlth, Dept Surg, Orebro, Sweden..
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2017 (English)In: Obesity, ISSN 1930-7381, E-ISSN 1930-739X, Vol. 25, no 8, p. 1451-1459Article in journal (Refereed) Published
Abstract [en]

Objective: To examine the change in use of hypnotics and/or sedatives after gastric bypass surgery or intensive lifestyle modification in adults with obesity.

Methods: Adults with obesity who underwent gastric bypass surgery or initiated intensive lifestyle modification between 2007 and 2012 were identified through the Scandinavian Obesity Surgery Registry and a Swedish commercial weight loss database. The two cohorts were matched on BMI, age, sex, education, history of hypnotics and/or sedatives use, and treatment year (surgery n = 20,626; lifestyle n = 11,973; 77% women, mean age 41 years, mean BMI 41 kg/m(2)). The proportion of participants with filled hypnotics and/or sedatives prescriptions was compared yearly for 3 years.

Results: In the matched treatment cohorts, 4% had filled prescriptions for hypnotics and/or sedatives during the year before treatment. At 1 year follow-up, following an average weight loss of 37 kg and 18 kg in the surgery and intensive lifestyle cohorts, respectively, this proportion had increased to 7% in the surgery cohort but remained at 4% in the intensive lifestyle cohort (risk ratio 1.7; 95% CI: 1.4-2.1); at 2 years, the proportion had increased to 11% versus 5% (risk ratio 2.0; 95% CI: 1.7-2.4); and at 3 years, it had increased to 14% versus 6% (risk ratio 2.2; 95% CI: 1.9-2.6).

Conclusions: Gastric bypass surgery was associated with increased use of hypnotics and/or sedatives compared with intensive lifestyle modification.

Place, publisher, year, edition, pages
WILEY , 2017. Vol. 25, no 8, p. 1451-1459
National Category
Medical and Health Sciences
Identifiers
URN: urn:nbn:se:uu:diva-333719DOI: 10.1002/oby.21908ISI: 000406782600023PubMedID: 28660652OAI: oai:DiVA.org:uu-333719DiVA, id: diva2:1157501
Funder
Swedish Research Council, 2013-3770, 2010-1078
Available from: 2017-11-16 Created: 2017-11-16 Last updated: 2017-11-16Bibliographically approved

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