Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Chemical induced effects on the developing nervous and immune systems: Protection against the harmful effects of chemicals on the development of the nervous and immune system, through better use of already planned animal studies
Responsible organisation
2017 (English)Report (Other academic)
Abstract [en]

Effects of chemicals on the developing brain and immune system are of high concern in the Nordic countries and EU. Since 2015, the Extended One Generation Reproductive Toxicity Study can be required under the REACH regulation, and if existing data shows specific concerns, tests for developmental neurotoxicity DNT and immunotoxicity DIT can be included. We considered that open literature may provide evidence to trigger DNT or DIT investigations. Search for information was performed for > 120 substances. Potentially relevant data was found for 40% of substances. Analysis of relatively few substances (19) for which the regulatory decision process has been finalized indicate limited impact of the data identified on triggering of DNT/DIT. Scientific and regulatory questions identified during this work are brought for the attention of the scientific communities and regulatory authorities.

Place, publisher, year, edition, pages
Copenhagen: Nordisk Ministerråd, 2017. , 25 p.
Series
Nordiske Arbejdspapirer, 2017:919
National Category
Chemical Sciences
Research subject
Environment; Chemicals
Identifiers
URN: urn:nbn:se:norden:org:diva-5013DOI: 10.6027/NA2017-919OAI: oai:DiVA.org:norden-5013DiVA: diva2:1154676
Available from: 2017-11-03 Created: 2017-11-03 Last updated: 2017-11-06

Open Access in DiVA

Download PDF(1063 kB)40 downloads
File information
File name FULLTEXT01.pdfFile size 1063 kBChecksum SHA-512
a71c0cee6218404b3c56bfbe209b563d29baca7fe93c658ca8160cf8e461a5b2898baf5e7059dd15373ba421fb6707aed5e8591dabe633ad8e96b1533563f0e7
Type fulltextMimetype application/pdf

Other links

Publisher's full text
Chemical Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 40 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 1067 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf