Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Påverkan på tal- och språkproduktion vid transkraniell magnetstimulering, TMS, hos personer med hjärntumör
Linköping University, Department of Clinical and Experimental Medicine, Division of Speech language pathology, Audiology and Otorhinolaryngology.
Linköping University, Department of Clinical and Experimental Medicine, Division of Speech language pathology, Audiology and Otorhinolaryngology.
2017 (Swedish)Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesisAlternative title
Effects on Speech and Language Production when Using Transcranial Magnetic Stimulation, TMS, in Patients with Brain Tumour (English)
Abstract [sv]

När en individ drabbas av hjärntumör kan det vara aktuellt med intervention i form av neurokirurgisk resektion. I de fall där neurokirurgisk intervention krävs görs om möjligt en preoperativ kartläggning av individens språk i syfte att identifiera känsliga språkområden i kortikala strukturer. I dagsläget används nTMS, navigerad transkraniell magnetstimulering, som genom att temporärt slå ut funktionen i specifika kortikala områden är en användbar metod för nämnda syfte. Patienten får då benämna bilder föreställande substantiv samtidigt som fokala delar i hjärnan stimuleras enskilt med magnetstimulering.

Syftet med föreliggande studie var att undersöka huruvida benämningsförmågan av substantiv förändrades vid nTMS hos personer med hjärntumör och på vilket sätt, samt om tumörlokalisation påverkade deltagarnas benämning vid nTMS-undersökning.

Samtliga deltagare i studien var patienter med hjärntumör som tidigare undersökts med nTMS på en neurofysiologisk klinik vid ett sjukhus i sydöstra Sverige. Undersökningarna filmades och har sedermera utgjort materialet till datainsamlingen i föreliggande studie. Analys gjordes på grupp- och populationsnivå, där grupperna skapades utifrån deltagarnas tumörlokalisationer.

Resultatet visar att benämningsförmågan förändras då ett antal olika språkliga fenomen uppkom vid preoperativ testning med nTMS. De fem vanligaste fenomenen på populationsnivå var tvekljud, latens, inskottsljud, uteblivet svar samt oprecis artikulation. Vid jämförelse på gruppnivå framkom att ingen signifikant skillnad föreligger avseende tumörlokalisation.

Resultatet kan tyda på att språkets neurofysiologi består av samarbetande komplexa nätverk. Resultatet kan också styrka teorier om tumörinducerad plasticitet.

Abstract [en]

When an individual is diagnosed with a brain tumour, intervention by neurosurgery might be needed. In case of neurosurgery, a preoperative assessment of the individual’s language functions is carried out, if possible, in order to identify sensitive language areas in cortical structures. Today, nTMS, navigated transcranial magnetic stimulation, is being used, which temporarily shuts down functions in specific cortical areas and thus is a useful method to fulfill this aim. The patient is asked to name a series of pictures representing nouns while focal parts of the brain is stimulated with magnetic stimulation.

The purpose of the present study was to examine whether the naming ability of nouns changed during nTMS in individuals with brain tumour and in what way, as well as whether the location of the tumour affected the participants naming abilities during nTMS.

All participants in the present study were patients with brain tumour, previously examined with nTMS in a neurophysiological clinic at a hospital in the South East of Sweden. The examinations were video recorded and have subsequently formed the material for data analysis in the present study. Analysis was made on group and population level. The groups were created based on the participants tumour localisation.

The result shows that the naming ability changes as a number of language related phenomenon aroused in the preoperative examination using nTMS. The five most common phenomena on population level were hesitation sound, latency, sound interjection, no response and inaccurate articulation. Comparison on group level revealed no significant difference regarding tumour location.

The result might indicate that the neurophysiology of language consists of collaborating complex networks. The result can also support theories regarding tumour induced plasticity.

Place, publisher, year, edition, pages
2017. , 40 p.
Keyword [en]
Brain tumour, TMS, language mapping, tumour induced plasticity, reorganization of language
Keyword [sv]
Hjärntumör, TMS, språklig kartläggning, tumörinducerad plasticitet, språklig reorganisation
National Category
Other Health Sciences
Identifiers
URN: urn:nbn:se:liu:diva-138096OAI: oai:DiVA.org:liu-138096DiVA: diva2:1106823
Subject / course
Master (one year thesis)/Speech and Language Pathology
Presentation
2017-05-15, Rönnen, Sandbäcksgatan 7, Linköping, 12:50 (Swedish)
Supervisors
Examiners
Available from: 2017-06-08 Created: 2017-06-08 Last updated: 2017-06-08Bibliographically approved

Open Access in DiVA

fulltext(1322 kB)19 downloads
File information
File name FULLTEXT01.pdfFile size 1322 kBChecksum SHA-512
4a8afcca8a3b1bab10f264425ab978851b4b94ada53a19f0109aba7d437db86733c5f6b6cab9a17dc6678020ab9013445e8b98156266ba8d4ca52e258641e013
Type fulltextMimetype application/pdf

Search in DiVA

By author/editor
Lindblad, CarolinaLöfström, Karin
By organisation
Division of Speech language pathology, Audiology and Otorhinolaryngology
Other Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 19 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 40 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf