Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Gene expression of behaviorally relevant genes in the cerebral hemisphere changes after selection for tameness in Red Junglefowl.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0001-5508-4465
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.
2017 (English)In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 12, no 5, e0177004Article in journal (Refereed) Published
Abstract [en]

The process of domestication in animals has led to alterations in behavior, physiology and phenotypic traits, changes that may be driven by correlations with reduced fear of humans. We used Red Junglefowl, ancestors of all domesticated chickens selected for either high or low fear of humans for five generations to study the effects of selection on gene transcription in the cerebral hemisphere, which is heavily involved in behaviour control. A total of 24 individuals from the parental generation as well as from the fifth selected generation were used. Twenty-two genes were significantly differentially expressed at p < 0.05 after false discovery rate (FDR) correction. Those genes that were upregulated in the low fearful animals were found to be involved in neural functions. Gene ontology and pathway analysis revealed enrichment for terms associated with behavioural processes. We conclude that five generations of divergent selection for high or low tameness has significantly changed gene expression patterns in the cerebral hemisphere in the Red Junglefowl population used here, which could underlie a range of changes in the domestic phenotype.

Place, publisher, year, edition, pages
Public Library of Science , 2017. Vol. 12, no 5, e0177004
National Category
Behavioral Sciences Biology
Identifiers
URN: urn:nbn:se:liu:diva-137300DOI: 10.1371/journal.pone.0177004ISI: 000401313700027PubMedID: 28481924OAI: oai:DiVA.org:liu-137300DiVA: diva2:1094767
Note

Funding agencies: research council Formas [221-2010-35]; Swedish Research Council VR [621-2011-4731]; European Research Council, ERC [322206 GENEWELL]; ERC [322206 GENEWELL]

Available from: 2017-05-11 Created: 2017-05-11 Last updated: 2017-06-13Bibliographically approved

Open Access in DiVA

fulltext(2896 kB)18 downloads
File information
File name FULLTEXT01.pdfFile size 2896 kBChecksum SHA-512
83baf369f07edb46b32fbbf9cbed647cd0a6836e7ae49b599584a6c2440b648d26f436f16108b76d93e73fb4af150ba46e97586adc699fa656d243c942866e79
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Beltéky, JohanEklund, BeatrixJensen, Per
By organisation
BiologyFaculty of Science & Engineering
In the same journal
PLoS ONE
Behavioral Sciences Biology

Search outside of DiVA

GoogleGoogle Scholar
Total: 18 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 101 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf