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Optimizing an Ultrasound Based Tissue Micro Engineering System: Optimering av ett Ultraljudsbaserat Cellmanipuleringssystem
KTH, School of Technology and Health (STH).
KTH, School of Technology and Health (STH).
2017 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

The usage of ultrasonic manipulation of cells enables a more in vivo-like study with maintained cell viability compared to ordinary systems based on 2D manipulation. The method can be applied for cell trapping and micro tissue engineering and has applications for medical and biological studies.  

The current system used at the Department of Applied Physics, Royal Institute of Technology, needs characterization and optimization regarding its subsystems. This thesis has studied the setup in order to map the origins of heat generation, to improve the system arrangement. As a result, an overview of affecting factors has been presented. The thesis is based on temperature and bead measurements with and without the use of an impedance matching circuit and with/without amplifiers. It was found that the system could be optimized with a smaller and less expensive amplifier reducing the overall system costs. The thesis also resulted in a proposition for further work to optimize the system with respect to its subsystems. 

Place, publisher, year, edition, pages
2017. , p. 62
Series
TRITA-STH ; 2017:2
National Category
Medical Engineering
Identifiers
URN: urn:nbn:se:kth:diva-202200OAI: oai:DiVA.org:kth-202200DiVA, id: diva2:1075376
Subject / course
Medical Engineering
Educational program
Master of Science - Medical Engineering
Supervisors
Examiners
Available from: 2017-02-21 Created: 2017-02-18 Last updated: 2017-02-21Bibliographically approved

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FRANS_KARLSSON_STUDENT_THESIS(3132 kB)109 downloads
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CiteExportLink to record
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