Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
B12 deficiency is common in infants and is accompanied by serious neurological symptons
regionjh.
Ă–stersund Hospital.
Regionjh.
2017 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 106, no 1, p. 101-104Article in journal (Refereed) Published
Abstract [en]

Aim

Adverse neurological symptoms have been linked to vitamin B12 deficiency in infants. This explorative study described the clinical presentation associated with vitamin B12 deficiency in this age group.

Methods

The study comprised infants who were born between 2004 and 2012 and were tested for vitamin B12 levels after they were admitted to a hospital with neurological symptoms at less than one year of age. Vitamin B12 deficiency was defined as low cobalamin in serum and/or increased homocysteine and/or increased methylmalonate. It was diagnosed according to the applicable International Classification of Diseases, 10th revision, and recorded as vitamin B12 deficiency in the medical records. All information was retrieved from medical records and compared to symptomatic infants with normal levels.

Results

Of the 121 infants tested, 35 had vitamin B12 deficiency and 86 had normal levels. Vitamin B12 deficiency was diagnosed at an average age of 1.7 months and was more common among boys. Seizures and apparent life-threatening events were the most common symptoms among infants with B12 deficiency compared to infants with normal levels.

Conclusion

Vitamin B12 deficiency was more common in infants than we expected and presented with severe symptoms, such as seizures and apparent life-threatening events.

Place, publisher, year, edition, pages
2017. Vol. 106, no 1, p. 101-104
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:miun:diva-29657DOI: 10.1111/apa.13625OAI: oai:DiVA.org:miun-29657DiVA, id: diva2:1057491
Available from: 2016-12-18 Created: 2016-12-18 Last updated: 2017-12-18Bibliographically approved

Open Access in DiVA

fulltext(180 kB)16 downloads
File information
File name FULLTEXT01.pdfFile size 180 kBChecksum SHA-512
fa331964f47092de095050e79ef33d8718b749e5e546d86837bf03e9fe29f56a6516aaf5d8b615b151ba5e4ba93264af34f443e669810e0ddeaba70bf0e888ce
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Axelsson, Inge
In the same journal
Acta Paediatrica
Pediatrics

Search outside of DiVA

GoogleGoogle Scholar
Total: 16 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 58 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf