Change search
ReferencesLink to record
Permanent link

Direct link
Hand grip strength is associated with forced expiratory volume in 1 second among subjects with COPD: report from a population-based cohort study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine. Division of Health and Rehabilitation, Department of Health Science, Luleå University of Technology, Luleå. (The Obstructive Lung disease in Northern Sweden Unit)
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine. (The Obstructive Lung disease in Northern Sweden Unit)
Show others and affiliations
2016 (English)In: The International Journal of Chronic Obstructive Pulmonary Disease, ISSN 1176-9106, E-ISSN 1178-2005, Vol. 11, 2527-2534 p.Article in journal (Refereed) Published
Abstract [en]

Background: Cardiovascular diseases and skeletal muscle dysfunction are common comorbidities in COPD. Hand grip strength (HGS) is related to general muscle strength and is associated with cardiovascular disease and all-cause mortality, while the results from small selected COPD populations are contradictory. The aim of this population-based study was to compare HGS among the subjects with and without COPD, to evaluate HGS in relation to COPD severity, and to evaluate the impact of heart disease. Subjects and methods: Data were collected from the Obstructive Lung disease in Northern Sweden COPD study, where the subjects with and without COPD have been invited to annual examinations since 2005. In 2009-2010, 441 subjects with COPD (postbronchodilator forced expiratory volume in 1 second [FEV1]/vital capacity,0.70) and 570 without COPD participated in structured interviews, spirometry, and measurements of HGS. Results: The mean HGS was similar when comparing subjects with and without COPD, but those with heart disease had lower HGS than those without. When compared by Global Initiative for Chronic Obstructive Lung Disease (GOLD) grades, the subjects with GOLD 3-4 had lower HGS than those without COPD in both sexes (females 21.4 kg vs 26.9 kg, P=0.010; males 41.5 kg vs 46.3 kg, P=0.038), and the difference persisted also when adjusted for confounders. Among the subjects with COPD, HGS was associated with FEV1% of predicted value but not heart disease when adjusted for height, age, sex, and smoking habits, and the pattern was similar among males and females. Conclusion: In this population-based study, the subjects with GOLD 3-4 had lower HGS than the subjects without COPD. Among those with COPD, HGS was associated with FEV1% of predicted value but not heart disease, and the pattern was similar in both sexes.

Place, publisher, year, edition, pages
Dove Medical Press , 2016. Vol. 11, 2527-2534 p.
Keyword [en]
muscle strength, muscle strength dynamometer, pulmonary disease, COPD, heart diseases, idemiology
National Category
Respiratory Medicine and Allergy
Identifiers
URN: urn:nbn:se:umu:diva-127258DOI: 10.2147/COPD.S114154ISI: 000385205700001OAI: oai:DiVA.org:umu-127258DiVA: diva2:1045636
Available from: 2016-11-10 Created: 2016-11-03 Last updated: 2016-11-10Bibliographically approved

Open Access in DiVA

fulltext(1605 kB)24 downloads
File information
File name FULLTEXT01.pdfFile size 1605 kBChecksum SHA-512
d4aba4cc53f0b8ca52e1afd2242e18c1929e45241d81c79b74e857cfbbb4a6bc2bf91fdfff8d9f2318998d8c9ebba342a1ccdc38915672152f6e3128dc326de8
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Backman, HelenaLindberg, Anne
By organisation
Occupational and Environmental MedicineMedicine
In the same journal
The International Journal of Chronic Obstructive Pulmonary Disease
Respiratory Medicine and Allergy

Search outside of DiVA

GoogleGoogle Scholar
Total: 24 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 20 hits
ReferencesLink to record
Permanent link

Direct link