Change search
ReferencesLink to record
Permanent link

Direct link
Mixed cultures as model communities: hunting for ubiquitous microorganisms, their partners, and interactions
Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Genetics, Limnology.
2016 (English)In: Aquatic Microbial Ecology, ISSN 0948-3055, E-ISSN 1616-1564, Vol. 77, no 2, 79-85 p.Article in journal (Refereed) Published
Abstract [en]

Even though thousands of microbial strains have now been successfully cultivated and described, these only represent a small fraction of global microbial diversity. Moreover, many of the ubiquitous and abundant environmental microorganisms still defy axenic cultivation. Here, I present mixed cultures as a powerful tool to cultivate and study ubiquitous but hard-to-cultivate microorganisms. A mixed culture is a subsample from a complex natural community that contains 2 or more microbial strains. When cultivated together with their metabolic partners, these ubiquitous microorganisms can mutually satisfy metabolic dependencies just as they do in the environment. By reducing the complexity while keeping some diversity, mixed cultures can then be used as model communities. Furthermore, by combining the relative simplicity of these model communities with molecular and bioinformatics tools, the complex natural interactions could be deciphered one model community at a time. Ultimately, mixed cultures can be used to generate a working hypothesis to explore the microbial ecology and genetic population structures of the unseen vast majority of microorganisms.

Place, publisher, year, edition, pages
2016. Vol. 77, no 2, 79-85 p.
Keyword [en]
Microbial ecology, Mixed cultures, Model communities, Cultivation, Interactions, Dependencies, Auxotrophy
National Category
Ecology Microbiology
Identifiers
URN: urn:nbn:se:uu:diva-305955DOI: 10.3354/ame01789ISI: 000384308000002OAI: oai:DiVA.org:uu-305955DiVA: diva2:1043859
Available from: 2016-11-01 Created: 2016-10-24 Last updated: 2016-11-01Bibliographically approved

Open Access in DiVA

fulltext(217 kB)9 downloads
File information
File name FULLTEXT01.pdfFile size 217 kBChecksum SHA-512
7a129a3eed1105cba2b1f6cda322b78f6f6e97c40abe0e8e70c9473489e11ad6ae8690a30f28990d06cddad570925d1560c787980b4682b1e0df00321c629129
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Garcia, Sarahi L.
By organisation
Limnology
In the same journal
Aquatic Microbial Ecology
EcologyMicrobiology

Search outside of DiVA

GoogleGoogle Scholar
Total: 9 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 58 hits
ReferencesLink to record
Permanent link

Direct link