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The domesticated brain: genetics of brain mass and brain structure in an avian species.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.ORCID iD: 0000-0003-1262-4585
Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden.
Linköping University, Department of Physics, Chemistry and Biology, Biology. Linköping University, Faculty of Science & Engineering.
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2016 (English)In: Scientific Reports, ISSN 2045-2322, E-ISSN 2045-2322, Vol. 6Article in journal (Refereed) Published
Abstract [en]

As brain size usually increases with body size it has been assumed that the two are tightly constrained and evolutionary studies have therefore often been based on relative brain size (i.e. brain size proportional to body size) rather than absolute brain size. The process of domestication offers an excellent opportunity to disentangle the linkage between body and brain mass due to the extreme selection for increased body mass that has occurred. By breeding an intercross between domestic chicken and their wild progenitor, we address this relationship by simultaneously mapping the genes that control inter-population variation in brain mass and body mass. Loci controlling variation in brain mass and body mass have separate genetic architectures and are therefore not directly constrained. Genetic mapping of brain regions indicates that domestication has led to a larger body mass and to a lesser extent a larger absolute brain mass in chickens, mainly due to enlargement of the cerebellum. Domestication has traditionally been linked to brain mass regression, based on measurements of relative brain mass, which confounds the large body mass augmentation due to domestication. Our results refute this concept in the chicken.

Place, publisher, year, edition, pages
London: Nature Publishing Group, 2016. Vol. 6
National Category
Natural Sciences Genetics Zoology
Identifiers
URN: urn:nbn:se:liu:diva-131808DOI: 10.1038/srep34031ISI: 000384339600001PubMedID: 27687864OAI: oai:DiVA.org:liu-131808DiVA: diva2:1033584
Note

Funding agencies: Carl Tryggers Stiftelse; Swedish Research Council (VR); Swedish Research Council for Environment; Agricultural Sciences and Spatial Planning (FORMAS); European Research Council [GENEWELL 322206]

Available from: 2016-10-07 Created: 2016-10-07 Last updated: 2016-11-02Bibliographically approved

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