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Reducering av jodkontrastmedelsdosen vid DT pulmonell angiografi och risken för kontrastmedelsinducerad nefropati
2014 (Swedish)Independent thesis Basic level (professional degree), 10 credits / 15 HE creditsStudent thesis
Abstract [en]

Pulmonary embolism (PE) is an illness that can be life threatening and computer tomography pulmonary angiography (CTPA) is one of the most common ways to diagnose it. CTPA studies require iodine contrast media (CM) in order to establish the diagnosis of PE. CM is toxic to the kidney, which can cause contrast induced nephropathy (CIN).The primary purpose of this literature study is to examine the possibility of reducing the amount of CM at low-kV CTPA. Is it possible to reduce the contrast dose without causing the results of the examination being suboptimal.The secondary purpose is to study the risks of developing (CIN) after CTPA.Based on our purpose we developed two questions that were answered through a systematic literature review. This literature study included 11 scientific articles from various databases.In our literature review we have come to the conclusion that CM dose could be reduced to a certain extent by using a low - kV CTPA protocol without quality loss and sometimes even with improvement of image quality. CIN after a CTPA has yielded various results some studies pointed out that CIN was affected by various risk factors and that CIN became increasingly common. Other studies claimed that age did not affect the risk of CIN.After this study, we conclude that low-kV CTPA with reduced CM- dosage can provide optimal examinations results on patients less than 80kg.The studies have reduced the CM dose with 25-40%.The presence of CIN has given a variation of results and it was difficult to draw a conclusion of exactly how much CM affected the incidence of CIN.

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URN: urn:nbn:se:ltu:diva-43974Local ID: 1c9e2575-adb7-497b-8341-fa3d135f5144OAI: diva2:1017248
Subject / course
Student thesis, at least 15 credits
Educational program
Diagnostic Radiology Nursing, bachelor's level
Validerat; 20140218 (global_studentproject_submitter)Available from: 2016-10-04 Created: 2016-10-04Bibliographically approved

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Långdahl, JosefinNilsson, Sofia

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