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Neural network theory and recent neuroanatomical findings indicate that inadequate nitric oxide synthase will cause autism
LuleƄ University of Technology, Department of Computer Science, Electrical and Space Engineering, Embedded Internet Systems Lab.
2003 (English)In: Knowledge-based intelligent information and engineering systems: 7th international conference ;proceedings / KES 2003, Oxford, UK, September 3 - 5, 2003. / [ed] Vasile Palade, Berlin: Encyclopedia of Global Archaeology/Springer Verlag, 2003, 1109-1114 p.Conference paper (Refereed)
Abstract [en]

Neural network theory indicates that inadequate expression of nitric oxide will cause narrow cortical neural columns, predicted on theoretical grounds and recently observed in autism. Another recent neuroanatomical finding in autism, early rapid growth of the cerebrum, may also be explained by inadequate expression of nitric oxide. Another long known neuroanatomical abnormality in autism, a reduced number of Purkinje cells in the Cerebellum, may also be caused, or aggravated, by inadequate expression of nitric oxide synthase. Some characteristics, such as motor impairments, sleep problems, deficit in aggression control and reduced nociception, which are not uncommon in autism, have been found in animal studies when nitric oxide synthase has been suppressed.

Place, publisher, year, edition, pages
Berlin: Encyclopedia of Global Archaeology/Springer Verlag, 2003. 1109-1114 p.
Lecture Notes in Computer Science, ISSN 0302-9743 ; 2774
Research subject
Industrial Electronics
URN: urn:nbn:se:ltu:diva-34142DOI: 10.1007/b12003Local ID: 842ce100-c7a1-11df-a707-000ea68e967bISBN: 978-3-540-40804-8OAI: diva2:1007392
International Conference on Knowledge-Based Intelligent Information and Engineering Systems : 03/09/2003 - 05/09/2003
Validerad; 2003; 20100924 (andbra)Available from: 2016-09-30 Created: 2016-09-30Bibliographically approved

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