In this chapter, the result of three research studies on meaning-making coping conducted among cancer patients in Sweden is used to highlight the effect of music in coping with cancer. The first research was a qualitative research aiming to study coping with cancer, through religious and spiritual means, from a cultural perspective. The second project was a quantitative study, which aimed to determine to what extent the result of the first study could be generalized to the cancer patients in Sweden. The third study had as its target to investigate the cancer patients’ own understanding of the role of music in coping. The results of these studies indicate the impact of culture in using music as a coping method when facing the psychological burden cancer brings with itself. The outcomes of the third study showed, besides the impact of culture, the individual characteristics of the music as a coping method.