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A Case Report of Improved Metabolic Control After Conversion From Everolimus to Cyclosporin A: Role of Adipose Tissue Mechanisms?
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Klinisk diabetologi och metabolism.
Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinska vetenskaper, Klinisk diabetologi och metabolism.
2014 (engelsk)Inngår i: Transplantation Proceedings, ISSN 0041-1345, E-ISSN 1873-2623, Vol. 46, nr 7, s. 2377-2380Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Background. New-onset diabetes after transplantation is associated with an increase in risk of graft failure, cardiovascular disease, and mortality. Therefore, it compromises the overall beneficial outcome of organ transplantation. Case Report. A patient with new-onset diabetes after renal transplantation showed glucose and lipid metabolism improvements after switching immunosuppressant from everolimus to cyclosporin A. A subcutaneous adipose tissue biopsy displayed changes in gene and protein expression that could contribute to the clinical improvement of hyperglycemia and dyslipidemia.

sted, utgiver, år, opplag, sider
2014. Vol. 46, nr 7, s. 2377-2380
HSV kategori
Identifikatorer
URN: urn:nbn:se:uu:diva-235513DOI: 10.1016/j.transproceed.2014.02.018ISI: 000342397500047OAI: oai:DiVA.org:uu-235513DiVA, id: diva2:761184
Konferanse
37th Congress of the Italian-Transplantation-Society (SITO), OCT 24-26, 2013, Bari, ITALY
Tilgjengelig fra: 2014-11-05 Laget: 2014-11-05 Sist oppdatert: 2018-01-11bibliografisk kontrollert

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