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Patients with postoperative atrial fibrillation have a doubled cardiovascular mortality
Örebro University, School of Health and Medical Sciences, Örebro University, Sweden. Department of Cardiothoracic Surgery and Anesthesiology, Örebro University Hospital, Örebro, Sweden.ORCID iD: 0000-0002-6913-0669
Örebro University, Örebro University School of Business. Department of Statistics and Epidemiology, Örebro University Hospital, Örebro, Sweden.
Örebro University, School of Health and Medical Sciences, Örebro University, Sweden. Department of Cardiology, Örebro University Hospital, Örebro, Sweden.
Örebro University, School of Health and Medical Sciences. Department of Cardiology, Örebro University Hospital, Örebro, Sweden.
2009 (English)In: Scandinavian cardiovascular journal : SCJ, ISSN 1651-2006, Vol. 43, no 5, p. 330-336Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: To investigate the impact of postoperative AF on late mortality and cause of death in CABG patients.

DESIGN: All CABG patients without preoperative AF surgically treated between January 1, 1997 and June 30, 2000 were included (N = 1419). Altogether, 419 patients (29.5%) developed postoperative AF. After a median follow-up of 8.0 years, survival data were obtained, causes of death were compared and Cox proportional hazard analysis was used to determine predictors of late mortality.

RESULTS: The total mortality was 140 deaths/419 patients (33.4%) in postoperative AF patients and 191 deaths/1 000 patients (19.1%) in patients without AF. Death due to cerebral ischemia (2.6% vs. 0.5%), myocardial infarction (7.4% vs. 3.0%), sudden death (2.6% vs. 0.9%), and heart failure (6.7% vs. 2.7%) was more common among postoperative AF patients. Postoperative AF was an age-independent risk indicator for late mortality with a hazard ratio (HR) of 1.56 (95% confidence interval 1.23-1.98).

CONCLUSIONS: Postoperative AF is an age-independent risk factor for late mortality in CABG patients, explained by an increased risk of cardiovascular death.

Place, publisher, year, edition, pages
2009. Vol. 43, no 5, p. 330-336
National Category
Cardiac and Cardiovascular Systems
Research subject
Cardiology
Identifiers
URN: urn:nbn:se:oru:diva-35560DOI: 10.1080/14017430802702291ISI: 000270288600009PubMedID: 19137475Scopus ID: 2-s2.0-77952583637OAI: oai:DiVA.org:oru-35560DiVA, id: diva2:730254
Note

Funding Agency:

Research Committee of Orebro University Hospital

Available from: 2014-06-27 Created: 2014-06-27 Last updated: 2017-10-17Bibliographically approved

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Ahlsson, AndersBodin, LennartFengsrud, EspenEnglund, Anders
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