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On the extent of quantum noise limitation in digital chest radiography
Linköpings universitet, Institutionen för medicin och vård, Radiofysik. Linköpings universitet, Hälsouniversitetet.
Linköpings universitet, Institutionen för medicin och vård, Radiofysik. Linköpings universitet, Hälsouniversitetet. Östergötlands Läns Landsting, Kirurgi- och onkologicentrum, Radiofysikavdelningen.ORCID-id: 0000-0003-3352-8330
Department of Physics, The Royal Marsden NHS Trust, UK.
Department of Radiation Physics, Göteborg, Sweden.
Vise andre og tillknytning
2004 (engelsk)Rapport (Annet vitenskapelig)
Abstract [en]

The aim for this work was to study to what extent the detection of nodules is quantum noise limited, based on the combined results from a nodule-detection clinical trial and a Monte Carlo computational model of a digital chest imaging system. The Monte Carlo computer program computes measures of physical image quality such as image contrast, C and signalto-noise ratio, SNR for nodules of any size. A computed radiography (CR) imaging system used simulated. The patient anterior-posterior thickness was 25 cm and nodules with diameters between 1-40 mm were included. The image contrast and SNR was calculated for 1600 (40x40) positions in the chest image and averaged over five anatomical regions of interest (lateral pulmonary, retrocardial, hilar, lower- and upper mediastinal regions). Threshold contrasts for each region, Cth, corresponding to Az=0.80 for detecting a 10 mm nodule, were deduced from the clinical trial. A threshold is also used for the quantum noise signal-to-noise ratio, SNRth. The model computes the diameter of a disk-shaped object that is required to comply with the two criteria: SNR≥SNRth and C≥Cth. A system is said to be quantum noise limited when the nodule size required to fulfil both criteria is not limited by the contrast but by the SNR. The required nodule diameter is largest in the hilar region (25 mm) and smallest in the lateral pulmonary region (11 mm). When the threshold SNRth=25 is used, the lower mediastinal region is quantum noise limited already at low speed classes (S>100). The hilar region is never quantum noise limited at realistic speed classes (S<1000). The accuracy of this model will be tested in the future by more sophisticated modelling of anatomical background and noise in the SNR-expression.

sted, utgiver, år, opplag, sider
Linköping: Linköping University Electronic Press , 2004. , s. 10
Serie
Report / Institutionen för radiofysik, Universitetet i Linköping, 1998- ; 98
HSV kategori
Identifikatorer
URN: urn:nbn:se:liu:diva-57865ISRN: LIU-RAD-R-099OAI: oai:DiVA.org:liu-57865DiVA, id: diva2:328158
Tilgjengelig fra: 2010-07-01 Laget: 2010-07-01 Sist oppdatert: 2015-03-20bibliografisk kontrollert

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On the extent of quantum noise limitation in digital chest radiography(213 kB)498 nedlastinger
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