The purpose of the paper is to determine the environmentally safe and economically feasible technology of biofertilizer production from the digestate including dewatering process. Methodological basis is based on the systematic approach to the determination of factors effected on the distribution of nutrients and pollutants between liquidand solid fractions after digestate separation. We studied modern technologies aimed at dewatering the digestateand reduction of its volume, showed their effectiveness. These technologies allow expanding the opportunities forcommercialization of the digestate, increasing the cost of its transportation and application to the soil instead ofcomplex fertilizers, using some valuable products. The results of the study showed that the ecological quality ofthe digestate is the highest as well as co-digested thermally pre-treated feedstock is used for solid-liquid separationin centrifuge with polymer addition as post-treatment approach to the flocculation. In order to increase efficiencyof biofertilizer application the technological scheme of production process of granular fertilizers from digestatewas proposed. Special feature of this scheme is in the use of phosphogypsum binder for the production of organomineral fertilizer that contributes phosphogypsum recycling in the waste management system.